ABCE1 and EIF3J

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ABCE1	EIF3J
Description		ATP binding cassette subfamily E member 1	eukaryotic translation initiation factor 3 subunit J
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Cytosolic Ribosome	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	Nucleotide Binding GTPase Activity Iron Ion Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Ribosomal Small Subunit Binding CTPase Activity Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Endoribonuclease Inhibitor Activity	Translation Initiation Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Translation Translational Initiation Translational Termination Regulation Of Translation Ribosome Disassembly Regulation Of Macromolecule Metabolic Process Negative Regulation Of Endoribonuclease Activity Protein Ufmylation Rescue Of Stalled Ribosome CAT Tailing Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation
Pathways		OAS antiviral response Interferon alpha/beta signaling PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		4 interacting genes: CEBPA EIF3J RNASE2 RNASEL	16 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 NFE2L2 SIAH1 TADA3 TPD52L1
Entrez ID		6059	8669
HPRD ID		03132	04883
Ensembl ID		ENSG00000164163	ENSG00000104131
Uniprot IDs		P61221	O75822
PDB IDs		6ZME 6ZVJ 7A09	2KRB 3BPJ 6YBW 6ZMW 6ZVJ
Enriched GO Terms of Interacting Partners?		RNA Nuclease Activity Fat Cell Differentiation Nuclear Matrix RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Nuclease Activity Ribonuclease A Activity Endonuclease Activity CHOP-C/EBP Complex White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Induction Of Bacterial Agglutination Response To Phenylpropanoid Defense Response To Virus Defense Response Fat Cell Proliferation RNA Metabolic Process Response To Lithium Ion Transcription By RNA Polymerase I Urea Metabolic Process Regulation Of Hematopoietic Stem Cell Proliferation Cellular Response To Lithium Ion HMG Box Domain Binding Nitrogen Cycle Metabolic Process White Fat Cell Differentiation Urea Cycle Interleukin-6-mediated Signaling Pathway Identical Protein Binding STAT Family Protein Binding Osteoblast Development Response To Virus Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Innate Immune Response In Mucosa	Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Translational Initiation Cytoplasmic Translational Initiation Translation Initiation Factor Activity Viral Translational Termination-reinitiation Eukaryotic Translation Initiation Factor 3 Complex, EIF3m IRES-dependent Viral Translational Initiation Translation Protein-RNA Complex Assembly Regulation Of Translation Regulation Of Protein Metabolic Process Regulation Of Translational Initiation Post-transcriptional Regulation Of Gene Expression Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Cytosol Rhythmic Process Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Primary Metabolic Process Macromolecule Biosynthetic Process Protein Catabolic Process Translation Initiation Factor Binding Execution Phase Of Apoptosis Regulation Of Protein Stability Positive Regulation Of Apoptotic Signaling Pathway Viral Process Positive Regulation Of Amide Metabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Macromolecule Metabolic Process Positive Regulation Of Glutathione Biosynthetic Process Negative Regulation Of Endoribonuclease Activity GTPase Activator Complex G-protein Gamma-subunit Binding Cytoplasm Protein-containing Complex Organization Regulation Of Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Phospholipase A2 Activator Activity Regulation Of Glutathione Biosynthetic Process Aflatoxin Catabolic Process Endoribonuclease Inhibitor Activity Regulation Of Endoribonuclease Activity RNA Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?