ABCE1

Description		ATP binding cassette subfamily E member 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Cytosolic Ribosome
	Molecular Function	Nucleotide Binding GTPase Activity Iron Ion Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Ribonucleoside Triphosphate Phosphatase Activity Ribosomal Small Subunit Binding CTPase Activity Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Endoribonuclease Inhibitor Activity
	Biological Process	Translation Translational Initiation Translational Termination Regulation Of Translation Ribosome Disassembly Regulation Of Macromolecule Metabolic Process Negative Regulation Of Endoribonuclease Activity Protein Ufmylation Rescue Of Stalled Ribosome CAT Tailing Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		OAS antiviral response Interferon alpha/beta signaling PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: CEBPA EIF3J RNASE2 RNASEL
Entrez ID		6059
HPRD ID		03132
Ensembl ID		ENSG00000164163
Uniprot IDs		P61221
PDB IDs		6ZME 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?		RNA Nuclease Activity Fat Cell Differentiation Nuclear Matrix RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Nuclease Activity Ribonuclease A Activity Endonuclease Activity CHOP-C/EBP Complex White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Induction Of Bacterial Agglutination Response To Phenylpropanoid Defense Response To Virus Defense Response Fat Cell Proliferation RNA Metabolic Process Response To Lithium Ion Transcription By RNA Polymerase I Urea Metabolic Process Regulation Of Hematopoietic Stem Cell Proliferation Cellular Response To Lithium Ion HMG Box Domain Binding Nitrogen Cycle Metabolic Process White Fat Cell Differentiation Urea Cycle Interleukin-6-mediated Signaling Pathway Identical Protein Binding STAT Family Protein Binding Osteoblast Development Response To Virus Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Innate Immune Response In Mucosa
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