ABCE1 and RNASEL

Number of citations of the paper that reports this interaction (PMID 7539425)
42

Data Source:
HPRD (in vitro)

		ABCE1	RNASEL
Gene Name		ATP-binding cassette, sub-family E (OABP), member 1	ribonuclease L (2,5-oligoisoadenylate synthetase-dependent)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Membrane	Cellular_component Mitochondrion Cytosol Nuclear Matrix
	Molecular Function	ATP Binding Ribonuclease Inhibitor Activity ATPase Activity Iron-sulfur Cluster Binding	RNA Binding Endoribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding RRNA Binding Metal Ion Binding
	Biological Process	RNA Catabolic Process Response To Virus Viral Process Negative Regulation Of Catalytic Activity	RRNA Processing MRNA Processing Protein Phosphorylation Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus Type I Interferon Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways			Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Multiple sclerosis ( 23412934)
Protein-Protein Interactions		2 interactors: RNASE2 RNASEL	3 interactors: ABCE1 AR TCF12
Entrez ID		6059	6041
HPRD ID		03132	01590
Ensembl ID		ENSG00000164163	ENSG00000135828
Uniprot IDs		P61221	Q05823 Q6AI46
PDB IDs			1WDY 4G8K 4G8L
Enriched GO Terms of Interacting Partners?		RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis Nucleic Acid Phosphodiester Bond Hydrolysis	Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Integrin Biosynthetic Process Regulation Of Integrin Biosynthetic Process
Tagcloud ?		aberrant codons decay dom34 drosophila e3 eliminate encounter erf1 eukaryotic homolog ligase ltn1 machineries mrnas nonstop nsd polypeptide proteasome recycling rescue ribosome ribosomes rqc stop translational triggered triggering uncovered	abnormality balancing blocking candidates controlling eif2 hematopoietic icsbp interferon involve irf isgs kappa kind knock leads looks mediates myelogenous oas oncogene phosphorylate pkr possibilities probably proliferative roles transduction undergoes
Tagcloud (Difference) ?		aberrant codons decay dom34 drosophila e3 eliminate encounter erf1 eukaryotic homolog ligase ltn1 machineries mrnas nonstop nsd polypeptide proteasome recycling rescue ribosome ribosomes rqc stop translational triggered triggering uncovered	abnormality balancing blocking candidates controlling eif2 hematopoietic icsbp interferon involve irf isgs kappa kind knock leads looks mediates myelogenous oas oncogene phosphorylate pkr possibilities probably proliferative roles transduction undergoes
Tagcloud (Intersection) ?