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RASGRF1 and RRAS2
Number of citations of the paper that reports this interaction (PubMedID
12384139
)
0
Data Source:
HPRD
(in vitro)
RASGRF1
RRAS2
Description
Ras protein specific guanine nucleotide releasing factor 1
RAS related 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Plasma Membrane
Growth Cone
Neuron Projection
Golgi Membrane
Endoplasmic Reticulum
Golgi Apparatus
Plasma Membrane
Focal Adhesion
Membrane
Extracellular Exosome
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Glutamate Receptor Binding
Nucleotide Binding
GTPase Activity
Protein Binding
GTP Binding
Hydrolase Activity
GDP Binding
Biological Process
Signal Transduction
Small GTPase-mediated Signal Transduction
Ras Protein Signal Transduction
Long-term Memory
Neuron Projection Development
Response To Endoplasmic Reticulum Stress
Positive Regulation Of Rac Protein Signal Transduction
Intracellular Signal Transduction
Negative Regulation Of MAPK Cascade
Positive Regulation Of MAPK Cascade
Type B Pancreatic Cell Proliferation
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Ras Protein Signal Transduction
Regulation Of Synaptic Plasticity
Regulation Of Neuronal Synaptic Plasticity
Osteoblast Differentiation
Signal Transduction
Ras Protein Signal Transduction
Cell Migration
Schwann Cell Migration
Positive Regulation Of Schwann Cell Migration
Pathways
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade
RND1 GTPase cycle
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Bronchopulmonary dysplasia (
23897914
)
Hand grip strength (
29691431
)
High myopia (
32428537
)
Myopia (
27182965
)
Pancreatic beta-cell glucose sensitivity (
32944759
)
Refractive error (
20835236
23396134
32231278
)
RR interval (heart rate) (
20031603
)
Spherical equivalent (joint analysis main effects and education interaction) (
27020472
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Alzheimer's disease (cognitive decline) (
23535033
)
Apolipoprotein A1 levels (
32203549
)
Brain morphology (MOSTest) (
32665545
)
Height (
31562340
)
Hip circumference adjusted for BMI (
34021172
)
Hip index (
34021172
)
Mitochondrial DNA levels (
25240745
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
31624269
)
Multiple sclerosis (
31604244
)
Refractive error (
32231278
)
Vitamin D levels (
25208829
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
20 interacting genes:
CEBPA
EHD4
GRIN2B
GRK2
HRAS
NTRK1
NTRK2
NTRK3
PRKACA
RAC1
RHOA
RRAS2
SNRNP70
SRC
SRPK2
STIP1
TNK2
USP8
YWHAB
YWHAE
33 interacting genes:
ACVR1
AFDN
AHSG
ARAF
ARHGEF2
BMPR1B
CREB3
FNTB
HDAC7
LGALS4
LINC00632
PAWR
PGGT1B
PIK3R1
PTPN1
RABAC1
RAF1
RALGDS
RAP1GDS1
RAPGEF1
RAPGEF3
RAPGEF4
RASGRF1
RASIP1
RASSF5
RGL3
RIN1
SMAD3
SMAD4
SMURF2
TRAF2
TRAF3
XRCC6
Entrez ID
5923
22800
HPRD ID
07362
02518
Ensembl ID
ENSG00000058335
ENSG00000133818
Uniprot IDs
A8K270
Q13972
Q8IUU5
P62070
PDB IDs
2ERY
9B4Q
9B4S
Enriched GO Terms of Interacting Partners
?
Intracellular Signaling Cassette
Nucleotide Binding
Neurotrophin Receptor Activity
Neurotrophin Binding
Regulation Of Cell Junction Assembly
Cellular Response To Growth Factor Stimulus
Signal Transduction
Protein Kinase Activity
Response To Growth Factor
Intracellular Signal Transduction
Cellular Response To Nerve Growth Factor Stimulus
Response To Nerve Growth Factor
Kinase Activity
Cell Surface Receptor Signaling Pathway
Protein Tyrosine Kinase Activity
Positive Regulation Of Signal Transduction
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Regulation Of Cell Projection Organization
Small GTPase-mediated Signal Transduction
Neuron Migration
Regulation Of Synapse Organization
Modulation Of Chemical Synaptic Transmission
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Cellular Component Biogenesis
Positive Regulation Of Cellular Component Organization
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Projection Organization
Regulation Of Cellular Component Organization
Regulation Of Signal Transduction
Phosphorylation
Mechanoreceptor Differentiation
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cell Migration
Neurotrophin Signaling Pathway
Protein Domain Specific Binding
Focal Adhesion
Positive Regulation Of Cell Junction Assembly
Plasma Membrane
Regulation Of Blood Circulation
Regulation Of Neuron Apoptotic Process
Perinuclear Region Of Cytoplasm
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
ATP Binding
Phosphoprotein Binding
Cell Motility
Endosome
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Regulation Of Cell Communication
Guanyl-nucleotide Exchange Factor Activity
Intracellular Signaling Cassette
Signal Transduction
Ras Protein Signal Transduction
Regulation Of Signal Transduction
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Regulation Of Apoptotic Process
Cytosol
Regulation Of Programmed Cell Death
SMAD Binding
Negative Regulation Of Signal Transduction
Regulation Of Protein Phosphorylation
Regulation Of Apoptotic Signaling Pathway
Small GTPase-mediated Signal Transduction
Cellular Response To Growth Factor Stimulus
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Bone Mineralization
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Phosphorylation
Regulation Of Protein Metabolic Process
Small GTPase Binding
Regulation Of Protein Modification Process
Intracellular Glucose Homeostasis
Enzyme-linked Receptor Protein Signaling Pathway
Activin Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Cellular Response To BMP Stimulus
Response To Growth Factor
Regulation Of Multicellular Organismal Process
Positive Regulation Of Multicellular Organismal Process
Negative Regulation Of Programmed Cell Death
Transforming Growth Factor Beta Receptor Activity, Type I
Regulation Of Cell Population Proliferation
Protein Prenyltransferase Activity
Apoptotic Signaling Pathway
Establishment Of Endothelial Barrier
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of SMAD Protein Signal Transduction
Positive Regulation Of Bone Mineralization
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
Endothelial Cell Development
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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