SUN2 and RPS20

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SUN2	RPS20
Gene Name		Sad1 and UNC84 domain containing 2	ribosomal protein S20
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Condensed Nuclear Chromosome Nuclear Envelope Integral Component Of Nuclear Inner Membrane Endosome Membrane Nuclear Membrane LINC Complex	Cytoplasm Cytosol Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear Envelope Organization Mitotic Spindle Organization Nuclear Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Centrosome Localization Cytoskeletal Anchoring At Nuclear Membrane Nuclear Matrix Anchoring At Nuclear Membrane	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Meiotic synapsis	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		5 interactors: HGS NRM RAB5A RAB5B RPS20	14 interactors: APP BARD1 ECT2 IL7R MPHOSPH6 MPP6 NDRG1 NRAS PAXIP1 PIK3CA PLEKHO1 RABAC1 REEP6 SUN2
Entrez ID		25777	6224
HPRD ID		15611	04728
Ensembl ID		ENSG00000100242
Uniprot IDs		B4E2A6 J3KQE0 Q9UH99	P60866
PDB IDs		3UNP 4DXR 4DXS 4DXT 4FI9	3J3A
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Endosomal Transport Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Cellular Protein Localization Rab Protein Signal Transduction Protein Transport Positive Regulation Of Exocytosis Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Regulation Of Exocytosis Cellular Localization Regulation Of Endocytosis Regulation Of Endosome Size Receptor Internalization Involved In Canonical Wnt Signaling Pathway Ras Protein Signal Transduction Plasma Membrane To Endosome Transport Positive Regulation Of Secretion Establishment Of Protein Localization To Organelle Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Localization To Membrane Protein Targeting To Lysosome Protein Localization To Lysosome Protein Targeting Cytoplasmic Translation Membrane Invagination Early Endosome To Late Endosome Transport Protein Localization To Organelle Protein Targeting To Vacuole Negative Regulation Of JAK-STAT Cascade Establishment Of Protein Localization To Vacuole Positive Regulation Of Smooth Muscle Cell Migration Endosome To Lysosome Transport Endosome Organization Small GTPase Mediated Signal Transduction Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Secretion Regulation Of Synaptic Vesicle Exocytosis Synaptic Vesicle Recycling Transport Regulation Of Synaptic Vesicle Transport Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Transport Receptor Internalization Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Filopodium Assembly	Positive Regulation Of Protein Metabolic Process Maturation Of 5.8S RRNA Response To Radiation Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Cell Activation Regulation Of Phosphorylation Regulation Of Protein Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Protein Kinase Activity Positive Regulation Of Cell Activation Visual Learning Regulation Of Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Visual Behavior Movement Of Cell Or Subcellular Component Response To Stress Positive Regulation Of Histone H3-K36 Methylation Regulation Of DNA Recombination Anatomical Structure Morphogenesis Regulation Of Immune Response DNA Damage Response, Signal Transduction By P53 Class Mediator Endothelial Cell Migration Positive Regulation Of Protein Modification Process Associative Learning Regulation Of Lymphocyte Activation Regulation Of Cell Cycle Regulation Of Cellular Amino Acid Metabolic Process Signal Transduction In Response To DNA Damage Hypomethylation Of CpG Island Synaptic Growth At Neuromuscular Junction Interleukin-7-mediated Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Blood Coagulation Regulation Of Multicellular Organism Growth Hemostasis Epithelial Cell Migration Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Intracellular Transport Epithelium Migration Cell Morphogenesis Intracellular Signal Transduction Positive Regulation Of Protein Kinase Activity Regulation Of Cell Activation Regulation Of Protein Phosphorylation Signal Transduction By P53 Class Mediator
Tagcloud ?		arrangement c2c12 cardiomyopathy centrosomal connects dreifuss dystrophy edmd emery exemplified gross identifiable linc microtubule modifier muscular myonuclear myopathies myotubes ne nucleation pericentrin phenotypically positioning rearward recapitulated repositioning segregating sun1	30s 5a 60s amongst atub bestkeeper cyp ef foundation gapdh genorm ginseng housekeeping iia ingredients medicines normalization normfinder optimum panax popular qcr qrt ranked reference rpl13 sar1 stems transcriptomics
Tagcloud (Difference) ?		arrangement c2c12 cardiomyopathy centrosomal connects dreifuss dystrophy edmd emery exemplified gross identifiable linc microtubule modifier muscular myonuclear myopathies myotubes ne nucleation pericentrin phenotypically positioning rearward recapitulated repositioning segregating sun1	30s 5a 60s amongst atub bestkeeper cyp ef foundation gapdh genorm ginseng housekeeping iia ingredients medicines normalization normfinder optimum panax popular qcr qrt ranked reference rpl13 sar1 stems transcriptomics
Tagcloud (Intersection) ?