RBSN and RAB5C

Number of citations of the paper that reports this interaction (PubMedID 34079125)
0

Data Source:
BioGRID (proximity labelling technology, pull down)

		RBSN	RAB5C
Description		rabenosyn, RAB effector	RAB5C, member RAS oncogene family
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GO Annotations	Cellular Component	Endosome Early Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Early Endosome Membrane Extracellular Exosome	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Small GTPase Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization	Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Endosomal Transport Regulation Of Endocytosis Plasma Membrane To Endosome Transport
Pathways		Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production	Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Respiratory syncytial virus (RSV) attachment and entry
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) Fibrinogen levels ( 26561523 28107422) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45	17 interacting genes: ALS2CL APP APPL2 EEA1 ERBB2 GLP1R HRAS INCA1 RABAC1 RBSN RIN2 RIN3 SGSM3 SNCA SREK1 TBC1D15 TBC1D17
Entrez ID		64145	5878
HPRD ID		15732	04947
Ensembl ID		ENSG00000131381	ENSG00000108774
Uniprot IDs		A8K5H3 Q9H1K0	P51148
PDB IDs		1YZM 1Z0J 1Z0K	4KYI
Enriched GO Terms of Interacting Partners?		G Protein Activity Endosome GTP Binding Intracellular Protein Localization Protein Transport Establishment Of Localization In Cell Endocytic Vesicle Intracellular Transport Regulation Of Vesicle-mediated Transport GDP Binding Establishment Of Protein Localization Early Endosome Membrane Cellular Localization Regulation Of Transport Synaptic Vesicle Vesicle-mediated Transport Cytoplasmic Vesicle GTPase Activity Early Endosome Positive Regulation Of Myoblast Fusion Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Recycling Endosome Membrane Melanosome Endosomal Transport Endomembrane System Nucleotide Binding Endosome Membrane Intracellular Protein Transport Glutamatergic Synapse Positive Regulation Of Intracellular Transport Regulation Of Cellular Component Organization Azurophil Granule Membrane Lysosomal Membrane Regulation Of Dendritic Spine Development Perinuclear Region Of Cytoplasm Organelle Assembly Hydrolase Activity Positive Regulation Of Endocytic Recycling Plasma Membrane To Endosome Transport Regulation Of Synaptic Transmission, Glutamatergic Endocytic Recycling Positive Regulation Of Transport Cilium Assembly Regulation Of Intracellular Transport Organelle Organization Regulation Of Synaptic Vesicle Cycle Cilium Organization Regulation Of Synapse Organization Vesicle Organization	Cytoplasmic Vesicle Vesicle-mediated Transport GTPase Activator Activity Regulation Of Long-term Neuronal Synaptic Plasticity Import Into Cell Endocytosis Endosomal Transport Small GTPase Binding Endosome Regulation Of Endocytosis Regulation Of Neuronal Synaptic Plasticity Early Endosome Intracellular Transport Intracellular Signaling Cassette Cellular Localization Glial Cell Development Establishment Of Localization In Cell Early Endosome Membrane Guanyl-nucleotide Exchange Factor Activity Presynapse Protein Tetramerization Regulation Of Cell Projection Assembly Schwann Cell Development Regulation Of Cilium Assembly Regulation Of Neurotransmitter Uptake Small GTPase-mediated Signal Transduction Cellular Response To Copper Ion Cellular Response To Growth Factor Stimulus Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of Protein Targeting To Membrane Amyloid Fibril Formation Regulation Of Vesicle-mediated Transport Regulation Of Cellular Component Organization Microglial Cell Activation Regulation Of Catalytic Activity Response To Growth Factor Recycling Endosome Regulation Of Protein Targeting To Membrane Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endocytosis Signal Transduction Glucagon-like Peptide 1 Receptor Activity Response To Desipramine
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