YBX1 and ANKRD2

Number of citations of the paper that reports this interaction (PMID 15136035)
34

Data Source:
HPRD (in vitro, in vivo)

		YBX1	ANKRD2
Gene Name		Y box binding protein 1	ankyrin repeat domain 2 (stretch responsive muscle)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytoplasmic Stress Granule Ribonucleoprotein Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex	Euchromatin Nucleus Cytosol PML Body Sarcomere I Band Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Poly(A) RNA Binding	Structural Constituent Of Muscle Titin Binding Protein Kinase B Binding RNA Polymerase II Sequence-specific DNA Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Splicing Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Negative Regulation Of Myoblast Differentiation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ACTA2 AKT1 ANKRD2 APBB1 CALM1 CSNK2A1 CTCF FBXO33 FMR1 FUS GSK3B HABP4 HIST1H1C HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCP2 LSM3 MAPK1 NFYB PCBP2 PCNA PRPF40A PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 UBC VEGFA	8 interactors: FAIM3 HBP1 PML TCAP TP53 TTN YBX1 ZBTB3
Entrez ID		4904	26287
HPRD ID		01095	12460
Ensembl ID		ENSG00000065978	ENSG00000165887
Uniprot IDs		P67809	Q9GZV1
PDB IDs		1H95
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Immune Response Immune Response Regulation Of Immune System Process Negative Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus Positive Regulation Of Metabolic Process Immune System Process Response To Stress Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Apoptotic Process Neurotrophin Signaling Pathway Innate Immune Response RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Growth Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Cell Activation Regulation Of Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Regulation Of Cell Differentiation System Development Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Translation Negative Regulation Of Biosynthetic Process Gene Expression Blood Coagulation Hemostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Wound Healing Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cell Growth Regulation Of RNA Metabolic Process Regulation Of Growth Posttranscriptional Regulation Of Gene Expression	Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Detection Of Muscle Stretch Myosin Filament Assembly Skeletal Muscle Thin Filament Assembly Skeletal Myofibril Assembly Cardiac Muscle Fiber Development Response To Muscle Stretch Cell Cycle Arrest Adult Heart Development Protein Import Positive Regulation Of Histone Deacetylation Cardiac Myofibril Assembly Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Deacetylation Cardiac Muscle Hypertrophy Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Cellular Senescence Actin-myosin Filament Sliding Muscle Filament Sliding Regulation Of Histone Deacetylation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Actin-mediated Cell Contraction Negative Regulation Of DNA Replication Detection Of Mechanical Stimulus Regulation Of Protein Deacetylation Muscle Fiber Development Response To Gamma Radiation Cardiac Muscle Contraction Sarcomere Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cardiac Muscle Tissue Morphogenesis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Actin Filament-based Movement Muscle Tissue Morphogenesis Regulation Of Tissue Remodeling Heart Contraction Protein Complex Assembly Cell Cycle Process Cardiac Muscle Cell Development Muscle Organ Morphogenesis Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint
Tagcloud ?		annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3	a165v a171t actinin2 alternatively cardiomyopathy compaction competition cypher cytoskeletal differs dilated homologue indication lethality lim mechanosensing motif multiprotein myofibrillar myopathy nomenclature pdz sarcomeres spliced striated sumoylation zasp zaspopathy zm
Tagcloud (Difference) ?		annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3	a165v a171t actinin2 alternatively cardiomyopathy compaction competition cypher cytoskeletal differs dilated homologue indication lethality lim mechanosensing motif multiprotein myofibrillar myopathy nomenclature pdz sarcomeres spliced striated sumoylation zasp zaspopathy zm
Tagcloud (Intersection) ?