YBX1 and ACTA2

Number of citations of the paper that reports this interaction (PMID 22619371)
3

Data Source:
BioGRID (unspecified method)

		YBX1	ACTA2
Gene Name		Y box binding protein 1	actin, alpha 2, smooth muscle, aorta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytoplasmic Stress Granule Ribonucleoprotein Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex	Extracellular Space Cytoplasm Cytosol Actin Cytoskeleton Smooth Muscle Contractile Fiber Protein Complex Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Poly(A) RNA Binding	ATP Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Splicing Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization	Muscle Contraction Regulation Of Blood Pressure Response To Virus Vascular Smooth Muscle Contraction Glomerular Mesangial Cell Development
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Smooth Muscle Contraction
Drugs
Diseases
GWAS			Immunoglobulin A ( 20694011)
Protein-Protein Interactions		41 interactors: ACTA2 AKT1 ANKRD2 APBB1 CALM1 CSNK2A1 CTCF FBXO33 FMR1 FUS GSK3B HABP4 HIST1H1C HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCP2 LSM3 MAPK1 NFYB PCBP2 PCNA PRPF40A PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 UBC VEGFA	16 interactors: CCT4 CCT5 CFL1 CREBBP DNASE1 EP300 GC MINK1 MYL1 MYOC PCYT1B PRKCD SHBG SNTA1 TMSB4X YBX1
Entrez ID		4904	59
HPRD ID		01095	00031
Ensembl ID		ENSG00000065978	ENSG00000107796
Uniprot IDs		P67809	D2JYH4 P62736
PDB IDs		1H95
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Immune Response Immune Response Regulation Of Immune System Process Negative Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus Positive Regulation Of Metabolic Process Immune System Process Response To Stress Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Apoptotic Process Neurotrophin Signaling Pathway Innate Immune Response RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Growth Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Cell Activation Regulation Of Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Regulation Of Cell Differentiation System Development Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Translation Negative Regulation Of Biosynthetic Process Gene Expression Blood Coagulation Hemostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Wound Healing Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cell Growth Regulation Of RNA Metabolic Process Regulation Of Growth Posttranscriptional Regulation Of Gene Expression	N-terminal Peptidyl-lysine Acetylation Regulation Of Actin Filament-based Process N-terminal Protein Amino Acid Acetylation Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Dephosphorylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Blood Coagulation N-terminal Protein Amino Acid Modification Hemostasis Negative Regulation Of Cytoskeleton Organization Regulation Of Cellular Response To Heat Platelet Activation Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Toxin Transport Binding Of Sperm To Zona Pellucida Positive Regulation Of Dephosphorylation Regulation Of Body Fluid Levels Sperm-egg Recognition Wound Healing Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of MAPK Cascade Regulation Of DNA-templated Transcription In Response To Stress Muscle System Process 'de Novo' Posttranslational Protein Folding Actin Filament-based Process Histone H2B Acetylation Positive Regulation Of Phospholipid Scramblase Activity Skeletal Muscle Hypertrophy Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process ERBB2-ERBB3 Signaling Pathway Regulation Of Vasoconstriction By Circulating Norepinephrine Primary Spermatocyte Growth 'de Novo' Protein Folding Developmental Process Cellular Response To Heat Cell Activation Cell-cell Recognition Termination Of Signal Transduction Response To Wounding Rhythmic Process Platelet Degranulation Negative Regulation Of Actin Filament Polymerization Regulation Of Cellular Component Size Positive Regulation Of Type I Interferon Production Positive Regulation Of Phospholipid Catabolic Process Glucosylceramide Catabolic Process ERBB2 Signaling Pathway
Tagcloud ?		annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3	attaining buffalo calves cirbp cryopreservation cryopreserved cyp11a1 d20s20 dairies dimethylsulfoxide dismutase2 dmso fbs fcc freezing germplasm homeobox leydig maturity pou pou5f1 protein3 rbm3 sod2 subfamily surviving testicular uncontrolled vim
Tagcloud (Difference) ?		annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3	attaining buffalo calves cirbp cryopreservation cryopreserved cyp11a1 d20s20 dairies dimethylsulfoxide dismutase2 dmso fbs fcc freezing germplasm homeobox leydig maturity pou pou5f1 protein3 rbm3 sod2 subfamily surviving testicular uncontrolled vim
Tagcloud (Intersection) ?