CREB3L2 and GCFC2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CREB3L2	GCFC2
Gene Name		cAMP responsive element binding protein 3-like 2	GC-rich sequence DNA-binding factor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Nucleolus U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription CAMP Response Element Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
	Biological Process	Chondrocyte Differentiation Transcription, DNA-templated ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cartilage Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Spliceosomal Complex Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Hippocampal atrophy ( 22745009)
Protein-Protein Interactions		12 interactors: CEP19 FBXW7 GAS7 GCFC2 GULP1 PTP4A1 PXN RGS16 RND1 UBA1 UBE2D3 ZNF212	2 interactors: ATXN1 CREB3L2
Entrez ID		64764	6936
HPRD ID		16391	01791
Ensembl ID		ENSG00000182158	ENSG00000005436
Uniprot IDs		Q68D60 Q70SY1	A4UHQ8 A4UHR0 B3KUM5 P16383 Q9BVX3
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cytoplasmic Transport Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Transport Positive Regulation Of Gene Expression Lung Alveolus Development Positive Regulation Of Cellular Biosynthetic Process Visual Learning Visual Behavior Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Postsynaptic Membrane Potential Associative Learning Chondrocyte Differentiation Establishment Of Localization In Cell Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER To Golgi Vesicle-mediated Transport ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Transcription, DNA-templated Adult Locomotory Behavior Membrane Depolarization Nuclear Export RNA Biosynthetic Process Cellular Localization Response To Unfolded Protein Learning Positive Regulation Of Cellular Metabolic Process Response To Endoplasmic Reticulum Stress Adult Behavior Organ Development Cartilage Development
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