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PEX2 and ERG28
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PEX2
ERG28
Description
peroxisomal biogenesis factor 2
ergosterol biosynthesis 28 homolog
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Peroxisome
Peroxisomal Membrane
Cytosol
Membrane
Cdc73/Paf1 Complex
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Transport Vesicle
Molecular Function
Protein Binding
Zinc Ion Binding
Protein Transmembrane Transporter Activity
Transferase Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Protein-macromolecule Adaptor Activity
Identical Protein Binding
Biological Process
Very Long-chain Fatty Acid Metabolic Process
Pexophagy
Protein Monoubiquitination
Fatty Acid Beta-oxidation
Peroxisome Organization
Protein Transport
Protein Import Into Peroxisome Matrix
Protein Import Into Peroxisome Matrix, Receptor Recycling
Protein Ubiquitination
Protein Destabilization
Cellular Response To Reactive Oxygen Species
Protein Unfolding
Protein Import Into Peroxisome Matrix, Substrate Release
Negative Regulation Of Fibroblast Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Response To Amino Acid Starvation
Lipid Metabolic Process
Steroid Biosynthetic Process
Steroid Metabolic Process
Sterol Biosynthetic Process
Pathways
E3 ubiquitin ligases ubiquitinate target proteins
Peroxisomal protein import
Peroxisomal protein import
Class I peroxisomal membrane protein import
Drugs
Diseases
Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
Fasting plasma glucose (
31170924
)
Height (
20881960
31562340
)
Infant length (
25281659
)
Menarche (age at onset) (
25231870
27182965
)
Nicotine dependence (
28440896
)
Systolic blood pressure response to hydrochlorothiazide in hypertension (
27802415
)
Interacting Genes
5 interacting genes:
APP
ERG28
PEX10
TLE1
USP2-AS1
127 interacting genes:
ALDH2
ANXA1
ANXA7
AQP2
AQP3
AQP6
ARL13B
BAIAP2
BCL2L13
BID
BTBD2
CCDC106
CCL18
CD53
CD74
CDC42
CDK5RAP2
CELF3
CLDN5
CLDN7
CLN8
COX17
COXFA4L2
CRADD
CREB1
CREB3
CREB3L1
CSTF2
CYB561
DYNLL1
EBP
ELOVL4
ERBB2
ERBB3
ERBB4
ERGIC3
FAM174A
FAM209A
FAS
FCGR2B
FFAR2
FXR1
FXYD3
GADD45A
GET1
GJB5
GPR152
GPR37L1
GPR42
GPX8
GSK3B
HMGB1
HNRNPH3
HNRNPUL1
HSD17B11
HSPE1
HTR2C
HYLS1
JAGN1
KCNJ6
KLHL20
LHFPL5
LMNA
LSM2
LYPD5
MAPK8IP2
MGST3
MPHOSPH6
MRM1
MRPL38
MRPS12
MS4A3
MSMO1
MTERF3
MTNR1B
MUC1
NAT9
NCR3LG1
NDUFA3
NR1H2
NSDHL
NSF
PAFAH1B3
PCDHA4
PDZK1IP1
PEX2
PFN1
PHYHIP
PIGY
POLE2
POLR2C
POLR3F
PPP1R8
PQBP1
PSCA
RAB27A
REEP4
RETREG3
RPS6KA6
S100A8
SAR1A
SAT1
SEPHS1
SERPINB9
SGPL1
SLC10A6
SLC26A6
SLC34A2
SLC71A2
SNRPB
SNRPG
SSMEM1
STOM
STX1A
SULT1E1
TFG
TK1
TLCD4
TM4SF19
TMEM106A
TMEM222
TMEM31
TMPRSS2
TSC22D1
TTR
ZFP64
ZNF24
Entrez ID
5828
11161
HPRD ID
01367
05201
Ensembl ID
ENSG00000164751
ENSG00000133935
Uniprot IDs
P28328
Q6FII3
Q86TW5
Q9UKR5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Acetylcholine Receptor Activator Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Amyloid-beta Complex
PTB Domain Binding
Growth Cone Lamellipodium
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Intermediate-density Lipoprotein Particle
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Response To Calcium Ion
Axon Midline Choice Point Recognition
Amylin Binding
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Amyloid Fibril Formation
Positive Regulation Of Toll Signaling Pathway
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Cellular Response To Norepinephrine Stimulus
Lipoprotein Particle
Growth Factor Receptor Binding
Main Axon
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Astrocyte Activation Involved In Immune Response
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Low-density Lipoprotein Particle Mediated Signaling
Target-directed MiRNA Degradation
Elongin Complex
Transport Vesicle
Regulation Of Spontaneous Synaptic Transmission
NMDA Selective Glutamate Receptor Signaling Pathway
Regulation Of Synapse Structure Or Activity
Regulation Of Toll Signaling Pathway
Protein Import Into Peroxisome Matrix, Substrate Release
Axon Choice Point Recognition
Early Endosome Membrane
Protein Binding
Membrane
Identical Protein Binding
Negative Regulation Of Apoptotic Process
Renal Water Transport
Negative Regulation Of Programmed Cell Death
Regulation Of Apoptotic Signaling Pathway
Polyol Transmembrane Transport
Regulation Of Apoptotic Process
Positive Regulation Of Cardiac Muscle Tissue Development
ERBB3:ERBB2 Complex
Regulation Of Secretion
Regulation Of Programmed Cell Death
Endoplasmic Reticulum Membrane
Regulation Of MAPK Cascade
Fluid Transport
Water Channel Activity
Positive Regulation Of MAPK Cascade
Positive Regulation Of Viral Entry Into Host Cell
Neuregulin Receptor Activity
Regulation Of Transport
Negative Regulation Of Hemopoiesis
Negative Regulation Of Secretion
Apolipoprotein A-I Receptor Binding
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Peptide Secretion
Apical Plasma Membrane
Positive Regulation Of Transport
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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