MT-ND1 and NDUFS7

Number of citations of the paper that reports this interaction (PubMedID 11418099)
0

Data Source:
HPRD (in vitro)

		MT-ND1	NDUFS7
Description		NADH dehydrogenase subunit 1	NADH:ubiquinone oxidoreductase core subunit S7
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Dendrite Mitochondrial Membrane Neuronal Cell Body Respiratory Chain Complex I	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Neuronal Cell Body Respiratory Chain Complex I Synaptic Membrane
	Molecular Function	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protease Binding NADH Dehydrogenase Activity Monooxygenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Response To Hypoxia Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Response To Xenobiotic Stimulus Mitochondrial Respiratory Chain Complex I Assembly Response To Hydroperoxide Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis
Pathways		Mitochondrial translation termination Respiratory electron transport Complex I biogenesis Mitochondrial protein degradation	Respiratory electron transport Complex I biogenesis
Drugs		NADH Methoxyflurane Halothane Desflurane Sevoflurane N-Formylmethionine Phenethyl Isothiocyanate	NADH
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes		13 interacting genes: BARD1 BRCA1 DHDDS FAT1 LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 SIRPA TSC1 TST	3 interacting genes: ARRB2 ENO2 MT-ND1
Entrez ID		4535	374291
HPRD ID		08365	03491
Ensembl ID		ENSG00000198888	ENSG00000115286
Uniprot IDs		P03886 U5Z754	F5H5N1 O75251 Q6ZS38 Q7LD69
PDB IDs		5XTC 5XTD	5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex BRCA1-B Complex Response To Ionizing Radiation Nuclear Ubiquitin Ligase Complex BRCA1-C Complex BRCA1-A Complex Ubiquitin-modified Histone Reader Activity Cellular Response To Ionizing Radiation DNA Recombination DNA Strand Resection Involved In Replication Fork Processing Regulation Of Cell Cycle G2/M Phase Transition Large Ribosomal Subunit Regulation Of DNA Damage Checkpoint Protein K6-linked Ubiquitination Cellular Response To Radiation Response To Radiation Condensed Chromosome Homologous Recombination DNA Repair Mitotic G2/M Transition Checkpoint Cellular Response To Stress Negative Regulation Of MRNA 3'-end Processing Establishment Of Epithelial Cell Apical/basal Polarity Involved In Camera-type Eye Morphogenesis Establishment Of Integrated Proviral Latency Memory T Cell Differentiation Negative Regulation Of Formation Of Translation Preinitiation Complex Polyprenol Biosynthetic Process Dehydrodolichyl Diphosphate Synthase Complex Ditrans,polycis-polyprenyl Diphosphate Synthase [(2E,6E)-farnesyl Diphosphate Specific] Activity Cytosolic Large Ribosomal Subunit Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Establishment Of Viral Latency Cyanate Catabolic Process 3-mercaptopyruvate Sulfurtransferase Activity Negative Regulation Of Cytoplasmic Translational Initiation Cellular Response To Type II Interferon Cellular Response To Interleukin-12 DNA Metabolic Process Cytoplasmic Ribonucleoprotein Granule Ubiquitin Ligase Complex DNA Damage Response Regulation Of G2/M Transition Of Mitotic Cell Cycle Ribonucleoprotein Complex DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination	Angiotensin Receptor Binding Positive Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Synaptic Transmission, Dopaminergic D1 Dopamine Receptor Binding Negative Adaptation Of Signaling Pathway Desensitization Of G Protein-coupled Receptor Signaling Pathway Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Response To Xenobiotic Stimulus Phosphopyruvate Hydratase Complex Purine Ribonucleotide Metabolic Process Phosphopyruvate Hydratase Activity ATP Metabolic Process Generation Of Precursor Metabolites And Energy Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Third Ventricle Development Positive Regulation Of Cardiac Muscle Cell Differentiation Protein Kinase B Binding Purine Nucleotide Metabolic Process Neuronal Cell Body NADH Dehydrogenase Activity Enzyme Binding G Protein-coupled Receptor Internalization Nucleotide Metabolic Process Lateral Ventricle Development Left/right Pattern Formation Positive Regulation Of Cardiocyte Differentiation
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