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MT-ND1 and DHDDS
Number of citations of the paper that reports this interaction (PubMedID
15110773
)
0
Data Source:
HPRD
(two hybrid)
MT-ND1
DHDDS
Description
NADH dehydrogenase subunit 1
dehydrodolichyl diphosphate synthase subunit
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Membrane
Dendrite
Mitochondrial Membrane
Neuronal Cell Body
Respiratory Chain Complex I
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Membrane
Dehydrodolichyl Diphosphate Synthase Complex
Molecular Function
NADH Dehydrogenase Activity
Protein Binding
NADH Dehydrogenase (ubiquinone) Activity
Prenyltransferase Activity
Protein Binding
Transferase Activity
Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups
Ditrans,polycis-polyprenyl Diphosphate Synthase [(2E,6E)-farnesyl Diphosphate Specific] Activity
Metal Ion Binding
Biological Process
Response To Hypoxia
Mitochondrial Electron Transport, NADH To Ubiquinone
Aerobic Respiration
Response To Xenobiotic Stimulus
Mitochondrial Respiratory Chain Complex I Assembly
Response To Hydroperoxide
Proton Motive Force-driven Mitochondrial ATP Synthesis
Proton Transmembrane Transport
Protein Glycosylation
Dolichyl Diphosphate Biosynthetic Process
Lipid Metabolic Process
Polyprenol Biosynthetic Process
Dolichyl Monophosphate Biosynthetic Process
Pathways
Mitochondrial translation termination
Respiratory electron transport
Complex I biogenesis
Mitochondrial protein degradation
Synthesis of dolichyl-phosphate
Defective DHDDS causes RP59
Drugs
NADH
Methoxyflurane
Halothane
Desflurane
Sevoflurane
N-Formylmethionine
Phenethyl Isothiocyanate
Diseases
Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Caffeine consumption from tea (
33287642
)
FEV1 (
30804560
)
Lung function (FVC) (
30804560
)
Peak expiratory flow (
30804560
)
Serum alkaline phosphatase levels (
33339817
)
Interacting Genes
13 interacting genes:
BARD1
BRCA1
DHDDS
FAT1
LIG4
MEOX2
NDUFS7
PAXIP1
RPL13A
RPL6
SIRPA
TSC1
TST
3 interacting genes:
LOX
MT-ND1
NPC2
Entrez ID
4535
79947
HPRD ID
08365
12183
Ensembl ID
ENSG00000198888
ENSG00000117682
Uniprot IDs
P03886
U5Z754
Q86SQ9
PDB IDs
5XTC
5XTD
6W2L
6Z1N
7PAX
7PAY
7PB0
7PB1
Enriched GO Terms of Interacting Partners
?
Histone H2AK127 Ubiquitin Ligase Activity
Histone H2AK129 Ubiquitin Ligase Activity
BRCA1-BARD1 Complex
BRCA1-B Complex
Response To Ionizing Radiation
Nuclear Ubiquitin Ligase Complex
BRCA1-C Complex
BRCA1-A Complex
Ubiquitin-modified Histone Reader Activity
Cellular Response To Ionizing Radiation
DNA Recombination
DNA Strand Resection Involved In Replication Fork Processing
Regulation Of Cell Cycle G2/M Phase Transition
Large Ribosomal Subunit
Regulation Of DNA Damage Checkpoint
Protein K6-linked Ubiquitination
Cellular Response To Radiation
Response To Radiation
Condensed Chromosome
Homologous Recombination
DNA Repair
Mitotic G2/M Transition Checkpoint
Cellular Response To Stress
Negative Regulation Of MRNA 3'-end Processing
Establishment Of Epithelial Cell Apical/basal Polarity Involved In Camera-type Eye Morphogenesis
Establishment Of Integrated Proviral Latency
Memory T Cell Differentiation
Negative Regulation Of Formation Of Translation Preinitiation Complex
Polyprenol Biosynthetic Process
Dehydrodolichyl Diphosphate Synthase Complex
Ditrans,polycis-polyprenyl Diphosphate Synthase [(2E,6E)-farnesyl Diphosphate Specific] Activity
Cytosolic Large Ribosomal Subunit
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle G2/M Phase Transition
Establishment Of Viral Latency
Cyanate Catabolic Process
3-mercaptopyruvate Sulfurtransferase Activity
Negative Regulation Of Cytoplasmic Translational Initiation
Cellular Response To Type II Interferon
Cellular Response To Interleukin-12
DNA Metabolic Process
Cytoplasmic Ribonucleoprotein Granule
Ubiquitin Ligase Complex
DNA Damage Response
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Ribonucleoprotein Complex
DNA Ligase (ATP) Activity
DNA Ligase IV Complex
Pro-B Cell Differentiation
T Cell Receptor V(D)J Recombination
Descending Aorta Development
Ascending Aorta Development
Organelle Envelope
Peptidyl-lysine Oxidation
Response To Xenobiotic Stimulus
Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Protein-lysine 6-oxidase Activity
Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor
Protein Oxidation
Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Mitochondrial Membrane
Cholesterol Storage
Glycolipid Transport
Sterol Binding
Regulation Of Isoprenoid Metabolic Process
Regulation Of Bone Development
Elastic Fiber Assembly
NADH Dehydrogenase Activity
Response To Oxidative Stress
Regulation Of Interleukin-1-mediated Signaling Pathway
Cellular Response To Chemokine
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Tagcloud (Intersection)
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