NSF and GOSR1

Number of citations of the paper that reports this interaction (PMID 8636227)
34

Data Source:
HPRD (in vivo)

		NSF	GOSR1
Gene Name		N-ethylmaleimide-sensitive factor	golgi SNAP receptor complex member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft Extracellular Vesicular Exosome	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane SNARE Complex
	Molecular Function	Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Rab GTPase Binding Protein Kinase Binding PDZ Domain Binding Protein Complex Binding ATPase Activity, Coupled Metal Ion Binding	SNAP Receptor Activity
	Biological Process	Positive Regulation Of Receptor Recycling Potassium Ion Transport Exocytosis Intra-Golgi Vesicle-mediated Transport Synaptic Transmission Vesicle-mediated Transport Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Golgi Vesicle Docking	ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Transport Retrograde Transport, Endosome To Golgi
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Parkinson's disease ( 19915575 21812969)
Protein-Protein Interactions		25 interactors: ARRB1 C14orf1 CD28 DRD2 EIF3E FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 KIAA1377 LUC7L2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA	8 interactors: APP EBI3 GABARAPL2 NAPA NSF SNAP25 STX5 USO1
Entrez ID		4905	9527
HPRD ID		03380	04936
Ensembl ID		ENSG00000073969	ENSG00000108587
Uniprot IDs		P46459	E9PCW1 O95249
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Fusion Membrane Organization Intracellular Transport Golgi Vesicle Transport Protein Localization Establishment Of Localization In Cell Protein Transport Synaptic Transmission Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cell-cell Signaling Intracellular Protein Transport Vesicle Fusion Intra-Golgi Vesicle-mediated Transport Cellular Protein Localization Neuron-neuron Synaptic Transmission Organelle Fusion Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Vesicle Organization Negative Regulation Of CAMP Biosynthetic Process Transport Mitochondrion Degradation Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Organelle Disassembly Synaptic Transmission, Glutamatergic Receptor Internalization Regulation Of Synaptic Vesicle Priming Regulation Of Protein Localization To Plasma Membrane Regulation Of Adenylate Cyclase Activity Regulation Of Vesicle-mediated Transport Regulation Of Cyclase Activity Regulation Of Insulin Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cytoplasmic Transport Regulation Of Cellular Localization G-protein Coupled Receptor Internalization Regulation Of Peptide Hormone Secretion Cellular Component Assembly Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Receptor Metabolic Process Vesicle Docking Post-Golgi Vesicle-mediated Transport Regulation Of CAMP Biosynthetic Process Membrane Docking Regulation Of Protein Localization Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Membrane Fusion Golgi Vesicle Transport Vesicle Docking Membrane Docking Vesicle-mediated Transport Membrane Organization Golgi Vesicle Docking Establishment Of Localization In Cell Vesicle Fusion Intra-Golgi Vesicle-mediated Transport Cellular Localization Organelle Fusion Intracellular Transport Vesicle Fusion With Golgi Apparatus Protein Transport Vesicle Organization Establishment Of Protein Localization Organelle Disassembly Transport Intracellular Protein Transport Exocytosis Protein Localization Post-Golgi Vesicle-mediated Transport ER To Golgi Vesicle-mediated Transport Secretion By Cell Cellular Protein Localization Synaptic Growth At Neuromuscular Junction SNARE Complex Disassembly Synaptic Transmission Secretion Regulation Of Secretion Collateral Sprouting In Absence Of Injury Golgi Disassembly Regulation Of Exocytosis Cytoplasmic Transport Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Synaptic Vesicle Priming Axon Choice Point Recognition Positive Regulation Of Metabolic Process Regulation Of Golgi Organization Golgi Inheritance Cell-cell Signaling Synaptic Vesicle Docking Neuron Remodeling Synaptic Vesicle Priming Early Endosome To Golgi Transport Cell Communication Regulation Of Protein Metabolic Process
Tagcloud ?		acetate alkylating amount apical associate attachment bound caco cellubrevin coimmunoprecipitation colocalizes connection define docking epithelium ethylmaleimide munc myristate phorbol predominantly quantity sec1 snap snare snares syntaxin thought verified vesicles
Tagcloud (Difference) ?		acetate alkylating amount apical associate attachment bound caco cellubrevin coimmunoprecipitation colocalizes connection define docking epithelium ethylmaleimide munc myristate phorbol predominantly quantity sec1 snap snare snares syntaxin thought verified vesicles
Tagcloud (Intersection) ?