CELSR3 and IFT140

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		CELSR3	IFT140
Gene Name		cadherin, EGF LAG seven-pass G-type receptor 3	intraflagellar transport 140
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Centrosome Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Primary Cilium Ciliary Tip
	Molecular Function	G-protein Coupled Receptor Activity Calcium Ion Binding Protein Binding	Molecular_function
	Biological Process	Neuron Migration Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Cilium Assembly	Organelle Organization Intraciliary Retrograde Transport Cilium Assembly Skeletal System Morphogenesis Retina Development In Camera-type Eye Protein Localization To Cilium Renal System Development Regulation Of Cilium Assembly
Pathways			Organelle biogenesis and maintenance Hedgehog 'off' state Signaling by Hedgehog Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA	4 interactors: CELSR3 NEK2 PFDN1 RANBP2
Entrez ID		1951	9742
HPRD ID		09179	11093
Ensembl ID		ENSG00000008300	ENSG00000187535
Uniprot IDs		Q9NYQ7	Q96RY7
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Organelle Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Histone H2A K63-linked Ubiquitination Late Endosome To Golgi Transport Negative Regulation Of Protein Complex Assembly Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Intracellular Distribution Of Mitochondria Negative Regulation Of Cytoskeleton Organization Adult Behavior Movement Of Cell Or Subcellular Component Regulation Of Protein K63-linked Ubiquitination Regulation Of Actin Filament Polymerization Intraciliary Retrograde Transport Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Clustering Of Voltage-gated Sodium Channels Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Heart Rate Cell Projection Morphogenesis Cytoskeletal Anchoring At Plasma Membrane Cell Part Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Hemidesmosome Assembly Organelle Organization Cellular Component Assembly Protein Localization To Cilium Regulation Of Cellular Component Organization Mitochondrion Distribution	Negative Regulation Of Centriole-centriole Cohesion Organelle Organization Regulation Of Centriole-centriole Cohesion Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cell Cycle Regulation Of Mitotic Centrosome Separation Protein Folding Negative Regulation Of Glucokinase Activity Organelle Assembly Centrosome Separation Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Axonal Fasciculation Protein Sumoylation
Tagcloud ?		avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Difference) ?		avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Intersection) ?