CELSR3 and SPTBN2

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		CELSR3	SPTBN2
Gene Name		cadherin, EGF LAG seven-pass G-type receptor 3	spectrin, beta, non-erythrocytic 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Space Cytoplasm Cytosol Spectrin Apical Plasma Membrane Cell Junction Neuronal Cell Body
	Molecular Function	G-protein Coupled Receptor Activity Calcium Ion Binding Protein Binding	Actin Binding Structural Constituent Of Cytoskeleton Phospholipid Binding
	Biological Process	Neuron Migration Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Axonal Fasciculation Regulation Of Protein Localization Cilium Assembly	Axon Guidance Synapse Assembly Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cerebellar Purkinje Cell Layer Morphogenesis Adult Behavior Multicellular Organism Growth Actin Filament Capping
Pathways			Interaction between L1 and Ankyrins Axon guidance MHC class II antigen presentation L1CAM interactions NCAM signaling for neurite out-growth Adaptive Immune System
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		11 interactors: CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA	9 interactors: ACTA1 ACTB ACTR1A APC CELSR3 DCTN1 MINK1 SPTA1 UNC13B
Entrez ID		1951	6712
HPRD ID		09179	05404
Ensembl ID		ENSG00000008300	ENSG00000173898
Uniprot IDs		Q9NYQ7	O15020
PDB IDs			1WJM 1WYQ
Enriched GO Terms of Interacting Partners?		Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Organelle Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Regulation Of Protein Complex Disassembly Negative Regulation Of Histone H2A K63-linked Ubiquitination Late Endosome To Golgi Transport Negative Regulation Of Protein Complex Assembly Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Intracellular Distribution Of Mitochondria Negative Regulation Of Cytoskeleton Organization Adult Behavior Movement Of Cell Or Subcellular Component Regulation Of Protein K63-linked Ubiquitination Regulation Of Actin Filament Polymerization Intraciliary Retrograde Transport Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Clustering Of Voltage-gated Sodium Channels Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Heart Rate Cell Projection Morphogenesis Cytoskeletal Anchoring At Plasma Membrane Cell Part Morphogenesis Neuronal Ion Channel Clustering Maintenance Of Cell Polarity Hemidesmosome Assembly Organelle Organization Cellular Component Assembly Protein Localization To Cilium Regulation Of Cellular Component Organization Mitochondrion Distribution	Organelle Organization Nervous System Development Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis System Development Neuron Development Cell Development Cell Morphogenesis Multicellular Organismal Development Anatomical Structure Development Neuron Differentiation Cell Projection Organization Axon Development Immune System Process Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Developmental Process Anatomical Structure Morphogenesis Cell Morphogenesis Involved In Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Generation Of Neurons Neurogenesis Homotypic Cell-cell Adhesion Regulation Of Protein Complex Assembly T Cell Differentiation In Thymus Cellular Component Assembly Positive Regulation Of Synaptic Vesicle Priming Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cytoskeleton Organization Negative Regulation Of Protein Complex Disassembly Cell Adhesion Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Protein Depolymerization Positive Regulation Of Synaptic Vesicle Exocytosis Skeletal Muscle Fiber Adaptation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Locomotion Single Organismal Cell-cell Adhesion Axonogenesis G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Complex Disassembly Actin Cytoskeleton Organization Response To Stimulus Regulation Of Cell Adhesion Vesicle-mediated Transport
Tagcloud ?		avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Difference) ?		avulsed avulsion biceps bpi brachial brachii c5 c7 corticospinal cst elbow electromyogram emg emx1 flexion fostering hamper innervation mbp motoneuron myelin nerves neuromuscular nmj nmjs plexus remyelination sheaths tore
Tagcloud (Intersection) ?