NUTF2 and NME4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUTF2	NME4
Description		nuclear transport factor 2	NME/NM23 nucleoside diphosphate kinase 4
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GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Membrane
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Phospholipid Binding Lipid Binding Kinase Activity Transferase Activity Protein-containing Complex Binding Metal Ion Binding GTPase Binding Phosphatidylglycerol Transfer Activity Mitochondrion-mitochondrion Outer Membrane Tether Activity Cardiolipin Binding
	Biological Process	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process Nucleotide Metabolic Process Protein Hexamerization Intermembrane Phospholipid Transfer
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Body mass index ( 26426971) Red blood cell traits ( 23446634)
Interacting Genes		48 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2	39 interacting genes: ABI2 AIRIM ARMC7 ATPAF2 C14orf119 CABP2 CABP5 CCDC102B CCDC57 CDKN2D CFAP206 CIB1 CIB3 CIDEB CLNK DTX2 HDAC7 HSF2BP LMO4 LSM8 MKRN3 MLH1 NME1 NME7 NUTF2 NXF1 POLR1C PSMB1 SOCS3 SPG21 SUV39H2 TNS4 TRAPPC2 TRAPPC2B TRIP13 TSSK3 TTC19 UBL5 ZBTB16
Entrez ID		10204	4833
HPRD ID		12050	03489
Ensembl ID		ENSG00000102898	ENSG00000103202
Uniprot IDs		P61970	A0A087WVT9 O00746
PDB IDs		1GY5	1EHW
Enriched GO Terms of Interacting Partners?		Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process	Protein Binding Male Meiotic Nuclear Division Male Germ Cell Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process 3'-5'-DNA Exonuclease Activity Female Meiosis I CTP Metabolic Process CTP Biosynthetic Process TRAPPII Protein Complex TRAPPIII Protein Complex Meiosis I Cell Cycle Process Nucleoside Diphosphate Kinase Activity TRAPP Complex Meiotic Nuclear Division Filopodium Tip Female Meiotic Nuclear Division
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