NUTF2 and CKMT1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUTF2	CKMT1B
Description		nuclear transport factor 2	creatine kinase, mitochondrial 1B
Image
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups
	Biological Process	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore	Phosphocreatine Biosynthetic Process
Pathways			Creatine metabolism
Drugs			Creatine Phosphocreatine
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		48 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2	12 interacting genes: ASB9 CALM1 CTNNA3 HPCA NUTF2 OCM PPP1R16A PSMC3 RXRG SFRP4 SLC25A5 VDAC1
Entrez ID		10204	1159
HPRD ID		12050	00424
Ensembl ID		ENSG00000102898	ENSG00000237289
Uniprot IDs		P61970	P12532
PDB IDs		1GY5	1QK1 9B04 9B05 9B0T 9B0U 9B14 9B16
Enriched GO Terms of Interacting Partners?		Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process	Mitochondrial Permeability Transition Pore Complex Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Catabolic Process Mitochondrial Nucleoid Regulation Of Mitophagy Negative Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Monoatomic Cation Transmembrane Transport Negative Regulation Of Sodium-dependent Phosphate Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Transmembrane Transporter Activity Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Contraction Negative Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Receptor Internalization Response To Ketamine Adenine Nucleotide Transmembrane Transporter Activity Mitochondrial ADP Transmembrane Transport ATP:ADP Antiporter Activity MMXD Complex Positive Regulation Of Macroautophagy Regulation Of Transport Adenine Transmembrane Transporter Activity Oxidative Phosphorylation Uncoupler Activity Adenine Transport Transmembrane Transporter Binding Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Transport Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Response To Calcium Ion Negative Regulation Of Monoatomic Ion Transport Regulation Of Heart Rate Negative Regulation Of Transmembrane Transport Regulation Of Monoatomic Ion Transport Regulation Of Striated Muscle Contraction Response To Aroclor 1254 Regulation Of Receptor-mediated Endocytosis Dendritic Spine Head
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