NUTF2 and PAX4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUTF2	PAX4
Description		nuclear transport factor 2	paired box 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome	Chromatin Nucleus Nucleoplasm
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore	Type B Pancreatic Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Sensory Organ Development Animal Organ Morphogenesis Cell Differentiation Forebrain Development Animal Organ Development Retina Development In Camera-type Eye
Pathways
Drugs
Diseases			Maturity onset diabetes of the young (MODY)
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Fruit consumption ( 32066663) Left-handedness ( 32989287) Metabolite levels ( 23823483) Nonsyndromic cleft palate ( 31609978) Type 2 diabetes ( 22158537 23532257 26818947 29632382 30718926 32499647 32794382) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		48 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2	14 interacting genes: AURKA CABP5 EIF4A3 FBXO2 GMCL1 NAIF1 NECAB1 NFYC NME7 NRXN3 NTM NUTF2 PSMC1 UBL5
Entrez ID		10204	5078
HPRD ID		12050	01333
Ensembl ID		ENSG00000102898	ENSG00000106331
Uniprot IDs		P61970	A0A1W2PPX4 J3KPG0
PDB IDs		1GY5
Enriched GO Terms of Interacting Partners?		Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process
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