NUTF2 and THAP11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUTF2	THAP11
Description		nuclear transport factor 2	THAP domain containing 11
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GO Annotations	Cellular Component	Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell Population Proliferation Electron Transport Chain Neuron Differentiation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Mitochondrial Transcription
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		48 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2	21 interacting genes: BBLN CASP3 CEBPA CFTR ECT2 HCFC1 HDAC1 HDAC3 HEMGN L3MBTL2 LRRC45 MCPH1 NUTF2 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52
Entrez ID		10204	57215
HPRD ID		12050	11629
Ensembl ID		ENSG00000102898	ENSG00000168286
Uniprot IDs		P61970	Q96EK4
PDB IDs		1GY5	2LAU 5AJS
Enriched GO Terms of Interacting Partners?		Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process	Nucleoplasm Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Binding Negative Regulation Of RNA Biosynthetic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Protein Lysine Delactylase Activity Negative Regulation Of Metabolic Process Regulation Of Cell Cycle Negative Regulation Of RNA Metabolic Process Chromatin Binding Histone Deacetylase Binding Histone Deacetylase Complex Transcription Corepressor Binding Transcription Repressor Complex Histone Deacetylase Activity, Hydrolytic Mechanism Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Protein Deacetylation Protein Lysine Deacetylase Activity General Transcription Initiation Factor Binding Response To Ketone Negative Regulation Of Biosynthetic Process Chromatin DNA Binding Rhythmic Process Protein-containing Complex Negative Regulation Of Myotube Differentiation Histone Deacetylase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Primary Metabolic Process Nucleus Sin3-type Complex Chromatin Organization Negative Regulation Of Stem Cell Population Maintenance Macromolecule Deacylation Microtubule Cytoskeleton Organization Involved In Mitosis Response To Glucocorticoid Mitotic Spindle Heterochromatin Formation NF-kappaB Binding Cellular Developmental Process Regulation Of Protein Stability Regulation Of Macromolecule Metabolic Process Cell Differentiation Response To Corticosteroid RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity
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