NUFIP2 and KRTAP1-3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUFIP2	KRTAP1-3
Description		nuclear FMR1 interacting protein 2	keratin associated protein 1-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Ribosome Cytoplasmic Stress Granule Membrane Nuclear Body	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	RNA Binding Protein Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process
Pathways			Keratinization
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Apolipoprotein B levels ( 32203549) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Headache ( 29397368) Heel bone mineral density ( 30598549) White blood cell count ( 32888494)
Interacting Genes		140 interacting genes: ADAMTSL4 AGRN ALPP AMOT CHRD COMP COXFA4L2 CRELD1 CRK CYP21A2 CYSRT1 DKK3 EFEMP1 EFEMP2 EGFL7 ESM1 FBLN1 FBLN2 FBLN5 FHL5 FMR1 FUCA2 GABARAP GABARAPL1 GAPDH GRN HNRNPC ICOS KPRP KRT31 KRT37 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1B LCE1D LCE1F LCE2B LCE2C LCE2D LCE3C LCE4A LCE5A LGALS13 LGALS8 LTBP3 LTBP4 MDFI MEGF11 MEGF6 MIR1-1 MIR106B MIR107 MIR128-1 MIR128-2 MIR138-2 MIR15B MIR17 MIR18A MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NBPF19 NELL1 NOTCH2NLA NOTCH3 OGT PCSK5 PEAR1 PEX5 PRDX5 RGS17 RGS19 RGS20 SLC22A17 SPRY2 STAB1 STAT3 STMN4 SYNPO TNFRSF4 TRAF1 TRIM42 TRIM55 TRIM63 VWF YPEL3 YWHAG	183 interacting genes: ADAM12 AGA ALDH3B1 ALPP ATG9A BCAM BHLHE40 BMP7 BTC C19orf25 C2orf68 CATSPER1 CELF5 CHIC2 CHRD CHRNG CLDN2 CMTM8 CNNM3 COA5 COL8A1 CRCT1 CREB5 CRH CRY2 CTNNBIP1 CXCL16 CYP21A2 CYSRT1 DAGLB DHRS1 DLGAP3 DMRT3 DOCK2 ECE1 EMC7 FBXW5 FZD10 GLP1R GLRX3 GLYAT GNE GRAP2 GSTP1 HCK HHEX HHIPL1 HOXA1 HOXB9 HOXC8 HPCAL1 HSD3B7 IGSF8 IL10 IL16 INPP5D INS ITGB4 ITGB5 JOSD1 KLHL38 KLK8 KPRP KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LONRF1 LRFN4 MAPKBP1 MOS MTNR1A MXD3 MXI1 MYPOP NAXD NECTIN2 NECTIN3 NID2 NMU NPBWR2 NPDC1 NR1D2 NUFIP2 OLFM2 OTX1 P3H3 PDE9A PDIA5 PHETA1 PHLDA1 PIGS PLEKHN1 PRF1 PRKAA2 PRKAB2 PRPF31 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAMAC RANBP3 RASD1 RPN1 RPS19BP1 SAPCD2 SDC3 SDCBP SELENOM SHFL SLC13A5 SLC22A23 SLC23A1 SLC39A7 SLC43A2 SLC5A5 SLC7A11 SMCP SPINT1 SPRY1 STK16 SUSD6 TACSTD2 TCAF1 TFAP2D TGFB1 THAP7 TNS2 UNC119 UTP23 UXT VASN VSTM4 WNT11 XCL2 YIPF3 YY1 ZDHHC1 ZFTRAF1 ZNF330 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF587 ZNF696 ZNF764 ZNF786 ZNF837
Entrez ID		57532	81850
HPRD ID		11764	12305
Ensembl ID		ENSG00000108256	ENSG00000221880
Uniprot IDs		Q7Z417	Q8IUG1
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Intermediate Filament Keratin Filament Post-transcriptional Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization Regulation Of Angiogenesis Negative Regulation Of Angiogenesis Regulation Of MRNA Stability Negative Regulation Of Vasculature Development Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Epidermis Development Extracellular Space Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Metabolic Process Keratinization Regulation Of Translation Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Cell Migration Negative Regulation Of Protein Metabolic Process Extracellular Matrix Structural Constituent Negative Regulation Of Interleukin-6-mediated Signaling Pathway	Epidermis Development Keratinization Protein Binding Intermediate Filament Keratin Filament Tissue Development Hair Cycle Susceptibility To T Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Animal Organ Morphogenesis Negative Regulation Of Defense Response Identical Protein Binding
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