NUFIP2 and MIRLET7F1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		NUFIP2	MIRLET7F1
Description		nuclear FMR1 interacting protein 2	microRNA let-7f-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Ribosome Cytoplasmic Stress Granule Membrane Nuclear Body	Extracellular Space RISC Complex Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process		Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of TOR Signaling Negative Regulation Of Interleukin-17 Production MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Apoptotic Process Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Amyloid-beta
Pathways
Drugs
Diseases
GWAS		Age at first birth ( 34211149) Apolipoprotein B levels ( 32203549) Depression ( 29700475) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Fasting glucose ( 34059833) Headache ( 29397368) Heel bone mineral density ( 30598549) White blood cell count ( 32888494)
Interacting Genes		140 interacting genes: ADAMTSL4 AGRN ALPP AMOT CHRD COMP COXFA4L2 CRELD1 CRK CYP21A2 CYSRT1 DKK3 EFEMP1 EFEMP2 EGFL7 ESM1 FBLN1 FBLN2 FBLN5 FHL5 FMR1 FUCA2 GABARAP GABARAPL1 GAPDH GRN HNRNPC ICOS KPRP KRT31 KRT37 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1B LCE1D LCE1F LCE2B LCE2C LCE2D LCE3C LCE4A LCE5A LGALS13 LGALS8 LTBP3 LTBP4 MDFI MEGF11 MEGF6 MIR1-1 MIR106B MIR107 MIR128-1 MIR128-2 MIR138-2 MIR15B MIR17 MIR18A MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NBPF19 NELL1 NOTCH2NLA NOTCH3 OGT PCSK5 PEAR1 PEX5 PRDX5 RGS17 RGS19 RGS20 SLC22A17 SPRY2 STAB1 STAT3 STMN4 SYNPO TNFRSF4 TRAF1 TRIM42 TRIM55 TRIM63 VWF YPEL3 YWHAG	93 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CELF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM47 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		57532	406888
HPRD ID		11764
Ensembl ID		ENSG00000108256	ENSG00000199072
Uniprot IDs		Q7Z417
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Intermediate Filament Keratin Filament Post-transcriptional Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization Regulation Of Angiogenesis Negative Regulation Of Angiogenesis Regulation Of MRNA Stability Negative Regulation Of Vasculature Development Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Epidermis Development Extracellular Space Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Metabolic Process Keratinization Regulation Of Translation Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Cell Migration Negative Regulation Of Protein Metabolic Process Extracellular Matrix Structural Constituent Negative Regulation Of Interleukin-6-mediated Signaling Pathway	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Processing Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Macromolecule Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus MiRNA Binding Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule RNA Splicing, Via Transesterification Reactions Regulation Of Translation Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Nucleoplasm Ribonucleoprotein Complex Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Stability Spliceosomal Complex Regulation Of MRNA Stability Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Macromolecule Metabolic Process MRNA Stabilization Negative Regulation Of RNA Catabolic Process MiRNA Processing Negative Regulation Of Macromolecule Metabolic Process RNA Stabilization Regulation Of Metabolic Process Negative Regulation Of Translation TRNA Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Ligase Activity Regulation Of Alternative MRNA Splicing, Via Spliceosome
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