KRTAP1-3 and MAPKBP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP1-3	MAPKBP1
Description		keratin associated protein 1-3	mitogen-activated protein kinase binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Cytoskeleton Mitotic Spindle Pole
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process		Negative Regulation Of Interleukin-8 Production Negative Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade Negative Regulation Of Defense Response To Bacterium Regulation Of Intracellular Signal Transduction
Pathways		Keratinization
Drugs
Diseases
GWAS			A body shape index ( 34021172) Appendicular lean mass ( 33097823) Diastolic blood pressure ( 27841878) Urinary albumin excretion ( 30220432) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		183 interacting genes: ADAM12 AGA ALDH3B1 ALPP ATG9A BCAM BHLHE40 BMP7 BTC C19orf25 C2orf68 CATSPER1 CELF5 CHIC2 CHRD CHRNG CLDN2 CMTM8 CNNM3 COA5 COL8A1 CRCT1 CREB5 CRH CRY2 CTNNBIP1 CXCL16 CYP21A2 CYSRT1 DAGLB DHRS1 DLGAP3 DMRT3 DOCK2 ECE1 EMC7 FBXW5 FZD10 GLP1R GLRX3 GLYAT GNE GRAP2 GSTP1 HCK HHEX HHIPL1 HOXA1 HOXB9 HOXC8 HPCAL1 HSD3B7 IGSF8 IL10 IL16 INPP5D INS ITGB4 ITGB5 JOSD1 KLHL38 KLK8 KPRP KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LONRF1 LRFN4 MAPKBP1 MOS MTNR1A MXD3 MXI1 MYPOP NAXD NECTIN2 NECTIN3 NID2 NMU NPBWR2 NPDC1 NR1D2 NUFIP2 OLFM2 OTX1 P3H3 PDE9A PDIA5 PHETA1 PHLDA1 PIGS PLEKHN1 PRF1 PRKAA2 PRKAB2 PRPF31 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAMAC RANBP3 RASD1 RPN1 RPS19BP1 SAPCD2 SDC3 SDCBP SELENOM SHFL SLC13A5 SLC22A23 SLC23A1 SLC39A7 SLC43A2 SLC5A5 SLC7A11 SMCP SPINT1 SPRY1 STK16 SUSD6 TACSTD2 TCAF1 TFAP2D TGFB1 THAP7 TNS2 UNC119 UTP23 UXT VASN VSTM4 WNT11 XCL2 YIPF3 YY1 ZDHHC1 ZFTRAF1 ZNF330 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF587 ZNF696 ZNF764 ZNF786 ZNF837	65 interacting genes: ADAM12 ADAMTSL4 ALG13 APTX CRYAA CTDSP1 CYSRT1 FOXN1 FXR1 FXR2 GLRX3 HOXA1 KEAP1 KPRP KRT31 KRT34 KRT35 KRT38 KRT40 KRT86 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP26-1 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 MAPK10 MAPK8 MAPK9 MDFI MEOX2 METTL15 MYOG NBPF19 NOTCH2NLA PLA2G10 PLSCR3 RBCK1 RGS20 SIAH1 SPRY2 SPRY3 TCF12 TCF4 TEKT5 TEX11 TRIM27 TRIM42 TRIP6 YPEL5 ZNF34
Entrez ID		81850	23005
HPRD ID		12305	17465
Ensembl ID		ENSG00000221880	ENSG00000137802
Uniprot IDs		Q8IUG1	O60336
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Protein Binding Intermediate Filament Keratin Filament Tissue Development Hair Cycle Susceptibility To T Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Animal Organ Morphogenesis Negative Regulation Of Defense Response Identical Protein Binding	Intermediate Filament Keratin Filament Structural Molecule Activity Structural Constituent Of Skin Epidermis Cytosol JUN Kinase Activity Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Epidermis Development MAP Kinase Activity Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Identical Protein Binding Supramolecular Fiber Organization Fc-epsilon Receptor Signaling Pathway Morphogenesis Of An Epithelium MRNA Destabilization Positive Regulation Of Long-term Neuronal Synaptic Plasticity RNA Destabilization Protein Binding Tissue Morphogenesis Positive Regulation Of MRNA Catabolic Process Regulation Of Circadian Rhythm
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?