KRTAP1-3 and RASD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP1-3	RASD1
Description		keratin associated protein 1-3	ras related dexamethasone induced 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus Cytoplasm Plasma Membrane Membrane Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Nucleotide Binding GTPase Activity Protein Binding GTP Binding G-protein Beta-subunit Binding
	Biological Process		Signal Transduction G Protein-coupled Receptor Signaling Pathway Nitric Oxide Mediated Signal Transduction Negative Regulation Of DNA-templated Transcription
Pathways		Keratinization
Drugs
Diseases
GWAS			A body shape index ( 34021172) Chronotype ( 30696823) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		183 interacting genes: ADAM12 AGA ALDH3B1 ALPP ATG9A BCAM BHLHE40 BMP7 BTC C19orf25 C2orf68 CATSPER1 CELF5 CHIC2 CHRD CHRNG CLDN2 CMTM8 CNNM3 COA5 COL8A1 CRCT1 CREB5 CRH CRY2 CTNNBIP1 CXCL16 CYP21A2 CYSRT1 DAGLB DHRS1 DLGAP3 DMRT3 DOCK2 ECE1 EMC7 FBXW5 FZD10 GLP1R GLRX3 GLYAT GNE GRAP2 GSTP1 HCK HHEX HHIPL1 HOXA1 HOXB9 HOXC8 HPCAL1 HSD3B7 IGSF8 IL10 IL16 INPP5D INS ITGB4 ITGB5 JOSD1 KLHL38 KLK8 KPRP KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LONRF1 LRFN4 MAPKBP1 MOS MTNR1A MXD3 MXI1 MYPOP NAXD NECTIN2 NECTIN3 NID2 NMU NPBWR2 NPDC1 NR1D2 NUFIP2 OLFM2 OTX1 P3H3 PDE9A PDIA5 PHETA1 PHLDA1 PIGS PLEKHN1 PRF1 PRKAA2 PRKAB2 PRPF31 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAMAC RANBP3 RASD1 RPN1 RPS19BP1 SAPCD2 SDC3 SDCBP SELENOM SHFL SLC13A5 SLC22A23 SLC23A1 SLC39A7 SLC43A2 SLC5A5 SLC7A11 SMCP SPINT1 SPRY1 STK16 SUSD6 TACSTD2 TCAF1 TFAP2D TGFB1 THAP7 TNS2 UNC119 UTP23 UXT VASN VSTM4 WNT11 XCL2 YIPF3 YY1 ZDHHC1 ZFTRAF1 ZNF330 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF587 ZNF696 ZNF764 ZNF786 ZNF837	38 interacting genes: ABI2 BHLHE41 CCDC57 CDR2L CYSRT1 EXOSC8 GNAI1 GNAI2 GNB1 HNRNPK HNRNPR KHDRBS3 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-9 KRTAP6-2 KRTAP6-3 MATR3 MDFI MKRN3 MTUS2 NBPF19 NOS1 NOS1AP NOTCH2NLA PLSCR1 PRDM5 PTPN21 RASAL3 RBMY1A1 RBMY1F RBMY1J TRIM37 WWP2
Entrez ID		81850	51655
HPRD ID		12305	08958
Ensembl ID		ENSG00000221880	ENSG00000108551
Uniprot IDs		Q8IUG1	Q9Y272
PDB IDs
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Protein Binding Intermediate Filament Keratin Filament Tissue Development Hair Cycle Susceptibility To T Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Animal Organ Morphogenesis Negative Regulation Of Defense Response Identical Protein Binding	Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Positive Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of MRNA Splicing, Via Spliceosome Heterotrimeric G-protein Complex Spliceosomal Complex Regulation Of RNA Splicing Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of RNA Splicing Regulation Of Membrane Repolarization During Action Potential Nucleic Acid Binding MRNA Metabolic Process MRNA Processing Guanyl Nucleotide Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of MRNA Metabolic Process Nucleolus Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Potassium Ion Transport Nitric Oxide Biosynthetic Process G-protein Beta/gamma-subunit Complex Binding Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization RNA Splicing Protein Binding
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