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KHDRBS2 and DOCK2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KHDRBS2
DOCK2
Gene Name
KH domain containing, RNA binding, signal transduction associated 2
dedicator of cytokinesis 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Cytoskeleton
Endomembrane System
Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
SH2 Domain Binding
Protein Heterodimerization Activity
Protein Binding
Rac GTPase Activator Activity
Rac Guanyl-nucleotide Exchange Factor Activity
T Cell Receptor Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Membrane Raft Polarization
Establishment Of T Cell Polarity
Immunological Synapse Formation
Myeloid Dendritic Cell Activation Involved In Immune Response
Chemotaxis
Small GTPase Mediated Signal Transduction
Viral Process
Actin Cytoskeleton Organization
Positive Regulation Of Rac GTPase Activity
Macropinocytosis
Positive Thymic T Cell Selection
Negative Thymic T Cell Selection
Alpha-beta T Cell Proliferation
Regulation Of Defense Response To Virus By Virus
Positive Regulation Of Phagocytosis
Pathways
HIV Infection
Host Interactions of HIV factors
The role of Nef in HIV-1 replication and disease pathogenesis
Factors involved in megakaryocyte development and platelet production
Nef and signal transduction
Drugs
Diseases
GWAS
Protein quantitative trait loci (
18464913
)
Protein quantitative trait loci (
18464913
)
Protein-Protein Interactions
29 interactors:
AEN
CATSPER1
CHTOP
CIRBP
DOCK2
EWSR1
GRB2
HBZ
HNRNPK
HNRNPR
KHDRBS3
LINC01018
MTA1
NABP1
NCOA5
NPDC1
PRMT1
PRPF31
PRR3
PTK6
RBM3
RBMX
SDCBP
SPG7
SULT1A3
TYK2
TYMSOS
YTHDC1
ZFC3H1
25 interactors:
CALCOCO2
CCNDBP1
CD247
CRKL
HNRNPK
KHDRBS1
KHDRBS2
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-8
KRTAP10-9
KRTAP4-2
KRTAP5-9
KRTAP9-2
KRTAP9-4
MDFI
MTUS2
NOTCH2NL
PAK2
PLSCR1
RAC1
RAC2
TRIM23
VAV1
Entrez ID
202559
1794
HPRD ID
13775
09121
Ensembl ID
ENSG00000112232
ENSG00000134516
Uniprot IDs
Q5VWX1
Q5XG91
Q92608
PDB IDs
2RQR
2YIN
3A98
3B13
Enriched GO Terms of Interacting Partners
?
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nucleobase-containing Compound Metabolic Process
Response To Ionizing Radiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Splicing
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
MRNA Processing
Gene Expression
Response To Radiation
Nitrogen Compound Metabolic Process
MRNA Metabolic Process
Cellular Process
Ribonucleoprotein Complex Assembly
Peptidyl-tyrosine Autophosphorylation
Response To Abiotic Stimulus
Regulation Of Metabolic Process
Cellular Metabolic Process
Response To Cold
Locomotion
Positive Regulation Of Metabolic Process
Myeloid Dendritic Cell Activation Involved In Immune Response
Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Protein Autoubiquitination
Cell Motility
Cell-cell Recognition
Cellular Component Assembly
Positive Regulation Of Translation
Regulation Of Protein Autoubiquitination
Membrane Raft Polarization
Movement Of Cell Or Subcellular Component
Regulation Of Cellular Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process
Alpha-beta T Cell Proliferation
Tyrosine Phosphorylation Of Stat5 Protein
Ribonucleoprotein Complex Biogenesis
T Cell Costimulation
Regulation Of Defense Response To Virus By Virus
Viral Process
Platelet Activation
Positive Regulation Of T Cell Activation
Regulation Of Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Immune System Process
Positive Regulation Of Cell-cell Adhesion
Regulation Of Hydrogen Peroxide Metabolic Process
Regulation Of Defense Response To Virus
Fc Receptor Signaling Pathway
Regulation Of Respiratory Burst
Positive Regulation Of Catalytic Activity
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Lamellipodium Assembly
Regulation Of T Cell Activation
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Activation
Regulation Of Cell Adhesion
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Immune Response
Positive Regulation Of Lamellipodium Organization
Signal Transduction
Regulation Of Cell-cell Adhesion
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of Neutrophil Chemotaxis
Regulation Of Lamellipodium Assembly
Positive Regulation Of Metabolic Process
Regulation Of Lymphocyte Activation
Response To Stress
Regulation Of Immune System Process
Positive Regulation Of Granulocyte Chemotaxis
Innate Immune Response
Blood Coagulation
Defense Response
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Hemostasis
Signaling
Response To Stimulus
Regulation Of Neutrophil Chemotaxis
Regulation Of Signal Transduction
Regulation Of Neutrophil Migration
Cell Communication
Regulation Of Immune Response
Tagcloud
?
abolish
atypical
beta2
chemotaxis
cpypp
dock5
fmlf
gef
gefs
gtpase
guanine
integrin
invading
kill
lacking
leukocytes
migrate
motile
net
nets
neutrophil
neutrophils
normally
participate
pathogens
pma
rac
ros
Tagcloud (Difference)
?
abolish
atypical
beta2
chemotaxis
cpypp
dock5
fmlf
gef
gefs
gtpase
guanine
integrin
invading
kill
lacking
leukocytes
migrate
motile
net
nets
neutrophil
neutrophils
normally
participate
pathogens
pma
rac
ros
Tagcloud (Intersection)
?