KHDRBS2 and NABP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KHDRBS2	NABP1
Description		KH RNA binding domain containing, signal transduction associated 2	nucleic acid binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol Site Of Double-strand Break SOSS Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding	DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Response To Ionizing Radiation Mitotic G2/M Transition Checkpoint
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)	Colorectal cancer ( 23266556)
Interacting Genes		54 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPA0 HNRNPK HNRNPLL HNRNPR KHDRBS3 LINC01018 LMNTD2 LNX1 MSI2 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBFOX2 RBM10 RBM14 RBM3 RBMX RFC3 RPP30 SDCBP SF1 SF3B4 SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837	10 interacting genes: COPS3 KHDRBS2 MKRN3 PURB QKI RBMX REL TFCP2 TP53 TRIM7
Entrez ID		202559	64859
HPRD ID		13775	08009
Ensembl ID		ENSG00000112232	ENSG00000173559
Uniprot IDs		Q5VWX1	Q96AH0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing MRNA Binding MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of MRNA Metabolic Process Spliceosomal Complex Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleus Regulation Of RNA Metabolic Process Nucleoplasm Regulation Of Primary Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Splicing Factor Binding Negative Regulation Of Macromolecule Metabolic Process Ribonucleoprotein Complex Regulation Of Metabolic Process Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Post-transcriptional Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Ionizing Radiation MRNA Stabilization Negative Regulation Of Biosynthetic Process Precatalytic Spliceosome	DNA-binding Transcription Factor Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process MRNA Binding MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Processing Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Splicing RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Type I Interferon Production Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Internal N(7)-methylguanine-containing RNA Reader Activity MRNA Transcription Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process T Cell Activation Involved In Immune Response Mononuclear Cell Differentiation Oligodendrocyte Apoptotic Process Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Myofibroblast Contraction Regulation Of MRNA Metabolic Process Negative Regulation Of MiRNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Cis-regulatory Region Sequence-specific DNA Binding Nucleoplasm DNA Binding Leukocyte Differentiation RNA Metabolic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Oxidative Stress-induced Premature Senescence Regulation Of MiRNA Metabolic Process Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Supraspliceosomal Complex Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription
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