KHDRBS2 and SULT1A3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KHDRBS2	SULT1A3
Description		KH RNA binding domain containing, signal transduction associated 2	sulfotransferase family 1A member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding	Aryl Sulfotransferase Activity Protein Binding Sulfotransferase Activity Transferase Activity Sulfate Binding Amine Sulfotransferase Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome	Ethanol Catabolic Process Catecholamine Metabolic Process Lipid Metabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Flavonoid Metabolic Process Thyroid Hormone Metabolic Process Epinephrine Metabolic Process Norepinephrine Metabolic Process Dopamine Metabolic Process Dopamine Catabolic Process Serotonin Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Cellular Response To Dopamine
Pathways		PTK6 Regulates Proteins Involved in RNA Processing	Cytosolic sulfonation of small molecules XBP1(S) activates chaperone genes Paracetamol ADME
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 27527254) Chronotype ( 30696823) Corneal astigmatism ( 30306274) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Esophageal adenocarcinoma ( 27527254) Presence of antiphospholipid antibodies ( 27098658) Protein quantitative trait loci ( 18464913)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		54 interacting genes: AEN BAHD1 BMP7 CATSPER1 CHTOP CIRBP CNNM3 DALRD3 DOCK2 EWSR1 FOXD4L3 GRAP2 GRB2 HBZ HHEX HNRNPA0 HNRNPK HNRNPLL HNRNPR KHDRBS3 LINC01018 LMNTD2 LNX1 MSI2 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PSMF1 PTK6 RBFOX2 RBM10 RBM14 RBM3 RBMX RFC3 RPP30 SDCBP SF1 SF3B4 SPG7 SULT1A3 TMEM14B TYK2 TYMSOS YTHDC1 ZFC3H1 ZNF497 ZNF581 ZNF688 ZNF837	6 interacting genes: APP KHDRBS2 NIF3L1 SHMT1 SMN1 TK1
Entrez ID		202559	6818
HPRD ID		13775	07199
Ensembl ID		ENSG00000112232	ENSG00000261052
Uniprot IDs		Q5VWX1	P0DMM9 Q1ET61
PDB IDs			1CJM 2A3R
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing MRNA Binding MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of MRNA Metabolic Process Spliceosomal Complex Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleus Regulation Of RNA Metabolic Process Nucleoplasm Regulation Of Primary Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Protein Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Splicing Factor Binding Negative Regulation Of Macromolecule Metabolic Process Ribonucleoprotein Complex Regulation Of Metabolic Process Identical Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of DNA-templated Transcription Post-transcriptional Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Ionizing Radiation MRNA Stabilization Negative Regulation Of Biosynthetic Process Precatalytic Spliceosome	Protein Tetramerization Deoxyribonucleoside Monophosphate Biosynthetic Process Protein Homooligomerization Protein Complex Oligomerization Identical Protein Binding Nucleoside Monophosphate Biosynthetic Process Pyrimidine-containing Compound Biosynthetic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Aldehyde-lyase Activity Cellular Response To Tetrahydrofolate Protein Homotetramerization Pyrimidine-containing Compound Metabolic Process Nucleoside Monophosphate Metabolic Process Protein-containing Complex Assembly Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Protein-containing Complex Organization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Perikaryon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Carnitine Biosynthetic Process Glycine Hydroxymethyltransferase Activity Glycine Biosynthetic Process From Serine DNA Synthesis Involved In Mitotic DNA Replication Thymidine Kinase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Glycine Biosynthetic Process DTMP Biosynthetic Process L-serine Catabolic Process
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