KHDRBS2 and AEN

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KHDRBS2	AEN
Gene Name		KH domain containing, RNA binding, signal transduction associated 2	apoptosis enhancing nuclease
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nucleolus Nuclear Membrane
	Molecular Function	Protein Binding Poly(A) Binding Poly(U) RNA Binding SH3 Domain Binding SH2 Domain Binding Protein Heterodimerization Activity	Nucleic Acid Binding Exonuclease Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		29 interactors: AEN CATSPER1 CHTOP CIRBP DOCK2 EWSR1 GRB2 HBZ HNRNPK HNRNPR KHDRBS3 LINC01018 MTA1 NABP1 NCOA5 NPDC1 PRMT1 PRPF31 PRR3 PTK6 RBM3 RBMX SDCBP SPG7 SULT1A3 TYK2 TYMSOS YTHDC1 ZFC3H1	33 interactors: AAMP AES EMD EXOSC8 GNPTAB HOMEZ IKZF1 KHDRBS2 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 LZTS2 MBNL1 MID2 MTUS2 NKX3-1 PDE4DIP PHC2 RALYL RBMY1A1 RBMY1F RPGRIP1 SSX2IP TRIM27 TRIM41 ZBTB43 ZBTB8A ZFP64 ZNF317 ZNF473
Entrez ID		202559	64782
HPRD ID		13775	08573
Ensembl ID		ENSG00000112232	ENSG00000181026
Uniprot IDs		Q5VWX1	Q8WTP8
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Response To Ionizing Radiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process MRNA Processing Gene Expression Response To Radiation Nitrogen Compound Metabolic Process MRNA Metabolic Process Cellular Process Ribonucleoprotein Complex Assembly Peptidyl-tyrosine Autophosphorylation Response To Abiotic Stimulus Regulation Of Metabolic Process Cellular Metabolic Process Response To Cold Locomotion Positive Regulation Of Metabolic Process Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Autoubiquitination Cell Motility Cell-cell Recognition Cellular Component Assembly Positive Regulation Of Translation Regulation Of Protein Autoubiquitination Membrane Raft Polarization Movement Of Cell Or Subcellular Component Regulation Of Cellular Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Alpha-beta T Cell Proliferation Tyrosine Phosphorylation Of Stat5 Protein Ribonucleoprotein Complex Biogenesis	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Viral Release From Host Cell Regulation Of RNA Splicing MRNA Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process MRNA Processing Positive Regulation Of Neutrophil Differentiation Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Androgen Secretion Regulation Of Viral Transcription Cellular Metabolic Process RNA Processing Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Estrogen Receptor Binding Regulation Of Wnt Signaling Pathway Response To Interleukin-1 Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Binding Negative Regulation Of Nucleic Acid-templated Transcription Histone MRNA 3'-end Processing RNA Splicing Biosynthetic Process Intraciliary Transport Involved In Cilium Morphogenesis
Tagcloud ?			abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal
Tagcloud (Difference) ?			abrupt appearing black characteristically circumferential compromised corrosive defenses demarcation duodenal endoscopically endoscopy esophageal esophagus gaining gastroesophageal ge globe hemorrhage hypoalbuminemia insult malnourishment morbidities multifactorial reflection sharp stricture striking universal
Tagcloud (Intersection) ?