PBXIP1 and CCNC

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PBXIP1	CCNC
Gene Name		pre-B-cell leukemia homeobox interacting protein 1	cyclin C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule	Nucleoplasm DNA-directed RNA Polymerase II, Holoenzyme Mediator Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding	Protein Binding Protein Kinase Binding
	Biological Process	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Transforming Growth Factor Beta Receptor Signaling Pathway Notch Signaling Pathway Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Loss of Function of TGFBR2 in Cancer PPARA activates gene expression Signaling by NOTCH1 HD Domain Mutants in Cancer Metabolism of lipids and lipoproteins Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 LBD Mutants in Cancer SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Generic Transcription Pathway Signaling by NOTCH1 Transcriptional regulation of white adipocyte differentiation Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer Fatty acid, triacylglycerol, and ketone body metabolism SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer Signaling by NOTCH TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer TGFBR1 KD Mutants in Cancer Loss of Function of TGFBR1 in Cancer NOTCH1 Intracellular Domain Regulates Transcription Signaling by TGF-beta Receptor Complex in Cancer Signaling by TGF-beta Receptor Complex Signaling by NOTCH1 PEST Domain Mutants in Cancer Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Constitutive Signaling by NOTCH1 PEST Domain Mutants SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		19 interactors: BRPF1 CCDC53 CCDC85B CCNC DAXX DEF6 DPPA2 GMCL1 GRB2 MDFI MORF4L1 PCBD2 PRKAA2 SGTA TSNAX UBQLN1 UBQLN4 ZMYND8 ZZZ3	32 interactors: CCNH CDK3 CDK8 CRX CTD DYDC1 ERCC3 ESR1 ESR2 FOXP2 GLYR1 GOLGA2 KRT13 KRT15 KRT31 LZTS2 MBIP MBP MCM2 MED8 MEOX2 MGST3 NEFL NMNAT1 PBXIP1 PNMA5 PUF60 RB1 TADA3 TP63 TRIM39 ZNF18
Entrez ID		57326	892
HPRD ID		17823	00456
Ensembl ID		ENSG00000163346	ENSG00000112237
Uniprot IDs		B4E1J0 Q96AQ6	E5RFK5 P24863 Q7Z4L3
PDB IDs			3RGF 4F6S 4F6U 4F6W 4F70 4F7J 4F7L 4F7N 4F7S 4G6L
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Expression Chromatin Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Activation Of JUN Kinase Activity Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Chromosome Organization Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Modification Positive Regulation Of JUN Kinase Activity Biosynthetic Process Regulation Of JUN Kinase Activity JNK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Histone Modification Embryonic Placenta Development Histone Acetylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Heterooligomerization Positive Regulation Of Stress-activated MAPK Cascade Protein Acetylation Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Metabolic Process Activation Of MAPK Activity Insulin Receptor Signaling Pathway Carnitine Shuttle Tetrahydrobiopterin Biosynthetic Process Regulation Of JNK Cascade	Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process DNA-templated Transcription, Initiation Intracellular Estrogen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Female Genitalia Development Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Prostate Gland Epithelium Morphogenesis Mitotic Cell Cycle Process Prostate Gland Morphogenesis Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Tissue Development G1/S Transition Of Mitotic Cell Cycle Genitalia Development Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Neuron Death Prostate Gland Development Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Vagina Development Uterus Development Negative Regulation Of Gene Expression Cell Cycle Chromosome Organization Chromatin Organization Cell Cycle Process Epithelial Cell Differentiation Involved In Prostate Gland Development Cell Death Death Nucleotide-excision Repair, DNA Damage Removal Regulation Of Gene Expression
Tagcloud ?			aa ascorbic ccnd1 cyp7a1 den diethylnitrosamine drinking enhances ercc expressions fed hepatectomy hepatocellular hepatocytes icr initiation intraperitoneally ka kojic ppm proliferating proliferative removed sacrificed subjected surviving thirds week weights
Tagcloud (Difference) ?			aa ascorbic ccnd1 cyp7a1 den diethylnitrosamine drinking enhances ercc expressions fed hepatectomy hepatocellular hepatocytes icr initiation intraperitoneally ka kojic ppm proliferating proliferative removed sacrificed subjected surviving thirds week weights
Tagcloud (Intersection) ?