SENP3

Description		SUMO specific peptidase 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Body MLL1 Complex
	Molecular Function	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity DeSUMOylase Activity
	Biological Process	Proteolysis Protein Desumoylation Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) IgM levels ( 23118916) Refractive error ( 32231278) Serum metabolite levels ( 33031748)
Interacting Genes		20 interacting genes: ADRB2 ATF7IP BECN1 CDCA8 CDK4 CDK6 CEP19 DNM1L EP300 HIC1 MED25 MTHFD1 NPM1 PARP1 PELP1 SUMO2 TRIM54 TRIM63 USP15 USP21
Entrez ID		26168
HPRD ID		08339
Ensembl ID		ENSG00000161956
Uniprot IDs		Q9H4L4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Transcription Regulator Complex Nucleoplasm Regulation Of Signal Transduction By P53 Class Mediator Regulation Of RNA Metabolic Process Protein-DNA Complex Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Organelle Organization Positive Regulation Of RNA Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Chromatin Remodeling Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Metaphase Plate Congression Cellular Response To UV Regulation Of Fibroblast Proliferation Regulation Of Muscle System Process Protein-containing Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Cell Cycle Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Light Stimulus Chromatin Organization Regulation Of Cellular Response To Stress Negative Regulation Of Small Molecule Metabolic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle G2/M Phase Transition Ubiquitin Protein Ligase Binding Negative Regulation Of ATP Metabolic Process Regulation Of Phosphorus Metabolic Process Mononuclear Cell Differentiation Regulation Of Gene Expression Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Macromolecule Metabolic Process Regulation Of Small Molecule Metabolic Process
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