ARMC7 and GIGYF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARMC7	GIGYF1
Description		armadillo repeat containing 7	GRB10 interacting GYF protein 1
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GO Annotations	Cellular Component	Spliceosomal Complex	Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	MRNA Processing RNA Splicing	Insulin-like Growth Factor Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Autoimmune thyroid disease ( 32581359) LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Pursuit maintenance gain in psychotic disorders ( 29064472) Resting heart rate ( 27798624)
Interacting Genes		71 interacting genes: ABI2 ABI3 AKAP19 APP CBY2 CCDC28B CCDC33 CDC42EP1 CFAP68 CHCHD3 CPSF6 CPSF7 DISC1 DPEP2NB DTX2 EFHC2 ESS2 GATA1 GIGYF1 HGS HOXA1 IKZF1 IKZF3 INCA1 KCTD13 KRT31 KRT34 KRT39 KRT40 KRT75 KRTAP13-1 KRTAP19-7 KRTAP6-3 LZTS2 MDFI NME4 PAK5 PIMREG PLEKHG4 PNMA6A REL RRP7A RUNDC3A SAXO1 SAXO5 SEPTIN14 SHISA6 SLAIN1 SPATC1L SPG21 SYF2 TASOR2 TCF4 TFIP11 TNFAIP1 TNNI1 TRIB3 TRIM27 TRIM42 TRIM54 USP54 VIM VPS37D YPEL3 ZBTB8A ZC2HC1C ZMAT5 ZNF140 ZNF426 ZNF669 ZNF764	33 interacting genes: AIRIM ANKRD10 ARMC7 ATN1 CBX8 CCDC57 CNOT9 CRACR2A ENKD1 FAM124B GRB10 GRB14 GRB7 KAT5 KIFC3 MCRS1 MNS1 NEK6 NFKBID PRKAA2 PRR35 RBM22 SCAF8 SCNM1 SMARCD1 SNRPB SNRPC SPAG8 STAC3 TCEA2 TLE5 TROAP TSHZ2
Entrez ID		79637	64599
HPRD ID		08649	10145
Ensembl ID		ENSG00000125449	ENSG00000146830
Uniprot IDs		J3KST7 J3KTE5 Q9H6L4	O75420
PDB IDs		7DVQ	5NVK 7RUQ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Supramolecular Fiber Organization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Protein Binding Cytoskeleton Organization Cytoskeleton Structural Molecule Activity MRNA Alternative Polyadenylation MRNA Cleavage Factor Complex	Nucleoplasm Spliceosomal Complex Negative Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Insulin Receptor Signaling Pathway Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Positive Regulation Of DNA Repair Spindle Pole Protein Binding Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cellular Response To Insulin Stimulus Insulin Receptor Signaling Pathway MRNA Splicing, Via Spliceosome U2-type Prespliceosome RNA Splicing U1 SnRNP Microtubule-based Process RNA Splicing, Via Transesterification Reactions Phosphatidylcholine Biosynthetic Process Regulation Of DNA Repair MRNA Metabolic Process Histone Acetyltransferase Complex Axonemal A Tubule Inner Sheath Positive Regulation Of Cation Channel Activity
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