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DNPEP

Description aspartyl aminopeptidase
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Blood Microparticle
Molecular Function
  • Aminopeptidase Activity
  • Protein Binding
  • Peptidase Activity
  • Metallopeptidase Activity
  • Zinc Ion Binding
  • Hydrolase Activity
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Proteolysis
  • Peptide Metabolic Process
Pathways
Drugs
  • Glutamic acid
Diseases
GWAS
  • Height ( 31562340)
  • Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
  • Triglyceride levels in HIV infection ( 33109212)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes 8 interacting genes: ADAMTSL4 AGT DGCR6 LNX1 MDFI MPP1 PAK5 SAT1
Entrez ID 23549
HPRD ID 09924
Ensembl ID ENSG00000123992
Uniprot IDs B7Z7F0 E5RIA4 E7ETB3 Q9ULA0
PDB IDs 4DYO
Enriched GO Terms of Interacting Partners?
  • Positive Regulation Of Angiotensin-activated Signaling Pathway
  • Extracellular Matrix
  • Renin-angiotensin Regulation Of Aldosterone Production
  • Positive Regulation Of Membrane Hyperpolarization
  • Response To Muscle Activity Involved In Regulation Of Muscle Adaptation
  • G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
  • Regulation Of Renal Output By Angiotensin
  • Type 2 Angiotensin Receptor Binding
  • Diamine N-acetyltransferase Activity
  • Spermidine Acetylation
  • Putrescine Catabolic Process
  • Spermidine Binding
  • Pigment Cell Development
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