RHOQ and COPG1

Number of citations of the paper that reports this interaction (PubMedID 12134073)
66

Data Source:
HPRD (in vivo)

		RHOQ	COPG1
Description		ras homolog family member Q	coat protein complex I subunit gamma 1
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GO Annotations	Cellular Component	Cytoplasm Actin Filament Plasma Membrane Membrane Golgi-associated Vesicle Membrane Membrane Raft Extracellular Exosome	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding Profilin Binding GTP Binding Protein Kinase Binding GBD Domain Binding	Structural Molecule Activity Protein Binding
	Biological Process	Endocytosis Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Cell Shape Establishment Of Cell Polarity Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Cellular Response To Insulin Stimulus Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Transcription By RNA Polymerase II GTP Metabolic Process Positive Regulation Of D-glucose Import Positive Regulation Of Filopodium Assembly Negative Regulation Of Protein Localization To Plasma Membrane	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Establishment Of Golgi Localization Organelle Transport Along Microtubule
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane RHO GTPases regulate CFTR trafficking RHOQ GTPase cycle	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs			S-(Dimethylarsenic)Cysteine
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: BANP CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 COPB1 COPG1 DOCK8 EXOC7 GOPC MORN4 NTAQ1 PARD6A PARD6B PFN1 PRKCI RAPGEF1 TRIP10 TRIP6 WASL ZNF417	23 interacting genes: ARCN1 ARF1 CDC42 CFTR COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 FILNC1 H2AX PPBP PTGES3 RHOQ RNF10 SACM1L SNCA SUMO2 TAPBP TMED10 WBP2 WEE2-AS1
Entrez ID		23433	22820
HPRD ID		05791	09887
Ensembl ID		ENSG00000119729	ENSG00000181789
Uniprot IDs		P17081 V9HWD0	Q9Y678
PDB IDs		2ATX	1R4X
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Cell Projection Organization Cytoplasm PAR Polarity Complex Positive Regulation Of Protein Polymerization Cytosol Regulation Of Cell Projection Assembly Regulation Of Actin Filament Polymerization Regulation Of Plasma Membrane Bounded Cell Projection Organization Small GTPase-mediated Signal Transduction Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cell Projection Organization Small GTPase Binding Rho Protein Signal Transduction Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Protein-containing Complex Assembly Cytoskeleton Tight Junction Regulation Of Cellular Component Size Regulation Of Actin Filament Organization Regulation Of Cell Shape Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cellular Component Biogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Positive Regulation Of Cellular Component Organization Cell Leading Edge Regulation Of Actin Cytoskeleton Organization Cell Cortex Actin Cytoskeleton Organization Plasma Membrane COPI Vesicle Coat Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Actin Filament-based Process COPI-coated Vesicle Membrane Regulation Of Protein-containing Complex Assembly Regulation Of Cell Morphogenesis Cell Junction Organization Endomembrane System Positive Regulation Of Organelle Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Bicellular Tight Junction Membrane Coat Intracellular Signaling Cassette Centriolar Satellite	COPI Vesicle Coat COPI-coated Vesicle Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum COPI-coated Vesicle Vesicle-mediated Transport Transport Vesicle Golgi Membrane Intra-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Endoplasmic Reticulum Membrane Establishment Of Localization In Cell Intracellular Protein Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Intracellular Protein Localization GBD Domain Binding Cellular Localization Golgi Apparatus Membrane Coat Cytoplasmic Vesicle Organelle Localization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Transport Glutamatergic Synapse Golgi Localization Golgi-associated Vesicle Membrane Adult Locomotory Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Transmission, Dopaminergic Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Long-term Synaptic Depression Positive Regulation Of Exocytosis Behavioral Response To Cocaine Vesicle-mediated Transport In Synapse Bounding Membrane Of Organelle Secretory Granule Membrane Regulation Of Dopamine Metabolic Process Dopamine Transport Regulation Of Neurotransmitter Uptake Establishment Of Organelle Localization Positive Regulation Of Monoatomic Ion Transmembrane Transport D-glucose Transmembrane Transport Positive Regulation Of Secretion By Cell Positive Regulation Of Filopodium Assembly Monoamine Transport Dopamine Metabolic Process Regulation Of Vesicle-mediated Transport GTPase Activity
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