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RHOQ and CDC42EP2
Number of citations of the paper that reports this interaction (PMID
10490598
)
24
Data Source:
BioGRID
(pull down, two hybrid)
HPRD
(two hybrid, in vitro)
RHOQ
CDC42EP2
Gene Name
ras homolog family member Q
CDC42 effector protein (Rho GTPase binding) 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Actin Filament
Plasma Membrane
Membrane Raft
Extracellular Vesicular Exosome
Cytoplasm
Plasma Membrane
Endomembrane System
Microtubule Cytoskeleton
Membrane
Molecular Function
GTPase Activity
Profilin Binding
GTP Binding
GBD Domain Binding
Opioid Peptide Activity
Rho GTPase Activator Activity
Protein Binding
GTP-Rho Binding
Biological Process
Small GTPase Mediated Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Cell Shape
Cortical Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Glucose Import
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Filopodium Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Actin Filament Organization
Regulation Of Cell Shape
Actin Cytoskeleton Organization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of Rho GTPase Activity
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
CDC42BPG
CDC42EP1
CDC42EP2
CDC42EP3
CDC42EP4
COPB1
COPG1
DOCK8
EXOC7
GOPC
PARD6A
PARD6B
PFN1
PRKCI
RAPGEF1
TRIP10
TRIP6
WASL
7 interactors:
ARHGAP26
CDC42
NME7
RHOQ
SEPT6
SEPT7
SNCA
Entrez ID
23433
10435
HPRD ID
05791
09363
Ensembl ID
ENSG00000149798
Uniprot IDs
P17081
O14613
PDB IDs
2ATX
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cell Projection Organization
Positive Regulation Of Pseudopodium Assembly
Regulation Of Cell Projection Assembly
Regulation Of Cell Projection Organization
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Positive Regulation Of Cellular Component Biogenesis
Golgi Vesicle Budding
Positive Regulation Of Protein Complex Assembly
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Membrane Budding
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Regulation Of Cytoskeleton Organization
Regulation Of Catalytic Activity
Intracellular Signal Transduction
Regulation Of Cellular Component Size
Actin Cytoskeleton Organization
Regulation Of Cellular Component Organization
Regulation Of Protein Complex Assembly
Small GTPase Mediated Signal Transduction
Localization Within Membrane
Vesicle-mediated Transport
Actin Filament-based Process
Positive Regulation Of Hydrolase Activity
Regulation Of Cell Shape
Tight Junction Assembly
Rho Protein Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Ras GTPase Activity
Cell Junction Assembly
Regulation Of GTPase Activity
Vesicle Organization
Cell-cell Junction Organization
Ras Protein Signal Transduction
Apical Junction Assembly
Organelle Organization
Positive Regulation Of Rho GTPase Activity
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Regulation Of Organelle Organization
Regulation Of Ras GTPase Activity
Golgi Vesicle Transport
Regulation Of Rho GTPase Activity
Positive Regulation Of Catalytic Activity
Organelle Organization
Regulation Of Filopodium Assembly
Positive Regulation Of Peptidyl-serine Phosphorylation
Regulation Of Cell Morphogenesis
Negative Regulation Of Thrombin Receptor Signaling Pathway
Positive Regulation Of Hydrogen Peroxide Catabolic Process
Positive Regulation Of Glutathione Peroxidase Activity
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Norepinephrine Uptake
Regulation Of Cytoskeleton Organization
Regulation Of Peptidyl-serine Phosphorylation
Cytokinesis
Regulation Of Cell Projection Assembly
Actin Cytoskeleton Organization
Small GTPase Mediated Signal Transduction
Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone
Regulation Of Embryonic Cell Shape
Positive Regulation Of Hair Follicle Cell Proliferation
Actin Filament-based Process
Microtubule-based Transport
Negative Regulation Of Protein Complex Assembly
Regulation Of Protein Stability
Cytoskeleton-dependent Intracellular Transport
Regulation Of Microtubule Cytoskeleton Organization
Negative Regulation Of Dopamine Metabolic Process
Submandibular Salivary Gland Formation
Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Serotonin Uptake
Actin Filament Branching
Negative Regulation Of Cellular Respiration
Positive Regulation Of Transport
Regulation Of Cell Shape
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of Microtubule-based Process
Negative Regulation Of Synaptic Transmission, Dopaminergic
Negative Regulation Of Oxidative Phosphorylation
Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Synapse Structural Plasticity
Regulation Of Cellular Component Organization
Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Membrane Organization
Establishment Of Golgi Localization
Response To Iron(II) Ion
Cellular Response To Copper Ion
Regulation Of Organelle Organization
Positive Regulation Of Metalloenzyme Activity
Positive Regulation Of Intracellular Transport
Regulation Of Neuron Apoptotic Process
Purine Nucleoside Metabolic Process
Regulation Of Synaptic Vesicle Recycling
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Tagcloud (Intersection)
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