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RHOQ and CDC42EP4
Number of citations of the paper that reports this interaction (PMID
10490598
)
24
Data Source:
HPRD
(two hybrid, in vitro)
RHOQ
CDC42EP4
Gene Name
ras homolog family member Q
CDC42 effector protein (Rho GTPase binding) 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Actin Filament
Plasma Membrane
Membrane Raft
Extracellular Vesicular Exosome
Cytoplasm
Plasma Membrane
Endomembrane System
Actin Cytoskeleton
Microtubule Cytoskeleton
Molecular Function
GTPase Activity
Profilin Binding
GTP Binding
GBD Domain Binding
Rho GTPase Activator Activity
GTP-Rho Binding
Poly(A) RNA Binding
Biological Process
Small GTPase Mediated Signal Transduction
Insulin Receptor Signaling Pathway
Regulation Of Cell Shape
Cortical Actin Cytoskeleton Organization
Cellular Response To Insulin Stimulus
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Glucose Import
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Filopodium Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Rho Protein Signal Transduction
Regulation Of Cell Shape
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Rho GTPase Activity
Pathways
Rho GTPase cycle
Signaling by Rho GTPases
Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
CDC42BPG
CDC42EP1
CDC42EP2
CDC42EP3
CDC42EP4
COPB1
COPG1
DOCK8
EXOC7
GOPC
PARD6A
PARD6B
PFN1
PRKCI
RAPGEF1
TRIP10
TRIP6
WASL
8 interactors:
APP
CDC42
FAM9B
LNX1
RHOQ
SRPK2
TGFBR1
WDR6
Entrez ID
23433
23580
HPRD ID
05791
08383
Ensembl ID
ENSG00000179604
Uniprot IDs
P17081
B2R6D8
B3KUS7
Q9H3Q1
PDB IDs
2ATX
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Cell Projection Organization
Positive Regulation Of Pseudopodium Assembly
Regulation Of Cell Projection Assembly
Regulation Of Cell Projection Organization
Positive Regulation Of Cytoskeleton Organization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Positive Regulation Of Cellular Component Biogenesis
Golgi Vesicle Budding
Positive Regulation Of Protein Complex Assembly
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Polymerization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Membrane Budding
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Regulation Of Cytoskeleton Organization
Regulation Of Catalytic Activity
Intracellular Signal Transduction
Regulation Of Cellular Component Size
Actin Cytoskeleton Organization
Regulation Of Cellular Component Organization
Regulation Of Protein Complex Assembly
Small GTPase Mediated Signal Transduction
Localization Within Membrane
Vesicle-mediated Transport
Actin Filament-based Process
Positive Regulation Of Hydrolase Activity
Regulation Of Cell Shape
Tight Junction Assembly
Rho Protein Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Ras GTPase Activity
Cell Junction Assembly
Regulation Of GTPase Activity
Vesicle Organization
Cell-cell Junction Organization
Ras Protein Signal Transduction
Apical Junction Assembly
Organelle Organization
Positive Regulation Of Rho GTPase Activity
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Regulation Of Organelle Organization
Regulation Of Ras GTPase Activity
Golgi Vesicle Transport
Regulation Of Rho GTPase Activity
Positive Regulation Of Catalytic Activity
Regulation Of Filopodium Assembly
Regulation Of Cell Cycle
Regulation Of Cell Projection Assembly
Regulation Of Protein Binding
Positive Regulation Of Gene Expression
Positive Regulation Of Filopodium Assembly
Regulation Of Binding
Positive Regulation Of Cell Projection Organization
Positive Regulation Of Cell Cycle
Positive Regulation Of Cellular Component Biogenesis
Angiogenesis
Positive Regulation Of Neuron Apoptotic Process
Blood Vessel Morphogenesis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neuron Death
Neuron Fate Commitment
Regulation Of ERBB Signaling Pathway
Regulation Of Cell Morphogenesis
Regulation Of Cell Projection Organization
Nuclear Speck Organization
Regulation Of Synapse Structure Or Activity
Blood Vessel Development
Vasculature Development
Regulation Of Cell Proliferation
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Wound Healing
Positive Regulation Of Cell Death
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Cellular Biosynthetic Process
Microtubule-based Transport
Cytoskeleton-dependent Intracellular Transport
Regulation Of Establishment Of Protein Localization
Cell Cycle Arrest
Response To Wounding
Submandibular Salivary Gland Formation
Collateral Sprouting In Absence Of Injury
Actin Filament Branching
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Intracellular Protein Transport
Positive Regulation Of Transport
Regulation Of Protein Kinase Activity
Positive Regulation Of Metabolic Process
Intracellular Signal Transduction
Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Synapse Structural Plasticity
Regulation Of Protein Localization
Regulation Of Kinase Activity
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Tagcloud (Intersection)
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