EPM2AIP1 and ZSCAN18

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		EPM2AIP1	ZSCAN18
Description		EPM2A interacting protein 1	zinc finger and SCAN domain containing 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytoplasmic Side Of Endoplasmic Reticulum Membrane	Nucleus
	Molecular Function	Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Glycogen Biosynthetic Process Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Subjective response to lithium treatment ( 26503763) Triglyceride levels ( 32203549)
Interacting Genes		47 interacting genes: ACTN1 APPL2 ARHGEF5 C1orf50 CBFA2T3 CCNB1IP1 CNTROB CPSF7 DTX3 EMP2 EPM2A FHL3 GFAP HSF2BP KCTD1 KCTD9 KRT16 KRT75 LDB2 LIN52 LNX1 MAD2L1 MEOX2 MX1 NOC4L OTUD7B PICK1 PRTFDC1 PSMA7 RBMY1F RBMY1J REL SERPINF1 SWSAP1 TFIP11 TNFAIP1 TNKS TRA2B TRIM50 TRIM54 USP54 VPS52 WEE2-AS1 ZBTB14 ZIM2 ZNF620 ZSCAN18	9 interacting genes: APP EPM2AIP1 FDXACB1 HOXD4 LIG4 SAFB2 ZNF174 ZNF446 ZSCAN22
Entrez ID		9852	65982
HPRD ID		07445	07802
Ensembl ID		ENSG00000178567	ENSG00000121413
Uniprot IDs		Q7L775	Q8TBC5
PDB IDs
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Positive Regulation Of MRNA Splicing, Via Spliceosome	DNA Binding Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Low-density Lipoprotein Particle Mediated Signaling DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation RRNA (uridine-N3-)-methyltransferase Activity Nucleus Central Nervous System Development Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Cell Activation Involved In Immune Response
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