CYBC1 and AHNAK2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYBC1	AHNAK2
Description		cytochrome b-245 chaperone 1	AHNAK nucleoprotein 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane T-tubule Sarcolemma
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Immune System Process Innate Immune Response Respiratory Burst After Phagocytosis	Regulation Of RNA Splicing
Pathways
Drugs
Diseases
GWAS			Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in normal cognition ( 29274321) Rheumatoid arthritis ( 24390342 30423114) Systemic lupus erythematosus ( 26663301 33272962)
Interacting Genes		65 interacting genes: ADIPOQ AGTRAP AHNAK2 AIG1 APCDD1L APOA2 APOL2 AQP10 AQP6 AQP8 ARLN BET1 C14orf180 CD53 CISD2 CLDN7 CLN6 COQ9 CPLX4 CREB3 CREB3L1 CYBB ERGIC3 ETS1 FAM209A GJA8 GPR151 GPR152 GPX8 HSD17B11 HSD17B13 INSIG2 JAGN1 KASH5 KIR2DL3 LAT LMNA LXN MFF MGST3 MTIF3 NINJ2 NOX3 NRM P2RX1 PDZK1IP1 PEX12 PLIN3 PLP1 PLP2 SCD SHISA4 SLC35H1 SLC71A2 SPN SSMEM1 STX2 THBD TM4SF19 TMEM128 TMEM80 TMPRSS2 TMX2 TRAM1L1 TSPAN12	16 interacting genes: ABLIM2 ASGR1 C3orf52 CTSA CYB5B CYBC1 FAM3C GABARAPL1 GABARAPL2 IGFBP5 PRAP1 SUMO2 TSPO2 UBIAD1 VAMP3 ZFPL1
Entrez ID		79415	113146
HPRD ID		14630	12261
Ensembl ID		ENSG00000178927	ENSG00000185567
Uniprot IDs		Q9BQA9	Q8IVF2
PDB IDs		8KEI	4CN0
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Water Channel Activity Channel Activity Negative Regulation Of Cholesterol Import Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On NAD(P)H, Oxygen As Acceptor Regulation Of Cholesterol Import One-carbon Compound Transport Water Transport Superoxide-generating NADPH Oxidase Activity Identical Protein Binding Fluid Transport Lipid Droplet Ammonium Channel Activity Urea Transmembrane Transport	Cellular Response To Nitrogen Starvation Endoplasmic Reticulum Phosphatidylethanolamine Binding GABA Receptor Binding Negative Regulation Of Skeletal Muscle Hypertrophy Beta-tubulin Binding Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Organelle Membrane Positive Regulation Of Triglyceride Transport 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity Autophagosome Maturation Autophagosome Membrane
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