CYBC1 and MTIF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYBC1	MTIF3
Description		cytochrome b-245 chaperone 1	mitochondrial translational initiation factor 3
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Mitochondrion
	Molecular Function	Protein Binding	Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ribosome Binding Ribosomal Small Subunit Binding
	Biological Process	Immune System Process Innate Immune Response Respiratory Burst After Phagocytosis	Translation Translational Initiation Ribosome Disassembly Mitochondrial Translational Initiation
Pathways			Mitochondrial translation initiation
Drugs
Diseases
GWAS			Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI x environmental factors (excluding physical activity) interaction ( 33654129) BMI x environmental factors (including physical activity) interaction ( 33654129) Body mass index ( 20935630 25673413 28892062) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate change in renal transplantation (recipient effect) ( 30920136) Night sleep phenotypes ( 27126917) Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603)
Interacting Genes		65 interacting genes: ADIPOQ AGTRAP AHNAK2 AIG1 APCDD1L APOA2 APOL2 AQP10 AQP6 AQP8 ARLN BET1 C14orf180 CD53 CISD2 CLDN7 CLN6 COQ9 CPLX4 CREB3 CREB3L1 CYBB ERGIC3 ETS1 FAM209A GJA8 GPR151 GPR152 GPX8 HSD17B11 HSD17B13 INSIG2 JAGN1 KASH5 KIR2DL3 LAT LMNA LXN MFF MGST3 MTIF3 NINJ2 NOX3 NRM P2RX1 PDZK1IP1 PEX12 PLIN3 PLP1 PLP2 SCD SHISA4 SLC35H1 SLC71A2 SPN SSMEM1 STX2 THBD TM4SF19 TMEM128 TMEM80 TMPRSS2 TMX2 TRAM1L1 TSPAN12	88 interacting genes: ADGRE2 APOD BCL2L1 BMP10 BPIFA1 BRICD5 CABP7 CD47 CDIPT CDS2 CGRRF1 CLDND2 CLEC7A CMTM5 COL4A5 COQ8A CTXN3 CXCL9 CYBC1 CYP4F2 EPGN FBXO7 FETUB FXYD3 FXYD6-FXYD2 HSFX1 HSFX2 HTATIP2 INSIG2 ITGB2 JAGN1 LAPTM4B LAT LDLR LHFPL5 MAPK1 MGST3 MRFAP1 MS4A1 NAT8 NDRG4 ORMDL1 ORMDL2 ORMDL3 PAXIP1 PEA15 PLN PLP1 PRH1 RPRM SCD SELENOK SERP1 SERP2 SERTM1 SIAH1 SNX2 SPANXN2 STARD4 STATH STRIT1 STX3 STX6 THBD THSD7B TMED8 TMEM109 TMEM11 TMEM128 TMEM147 TMEM176A TMEM218 TMEM239 TMEM242 TMEM243 TMEM254 TMEM42 TMEM97 TRARG1 TSPAN33 TUFM UNC50 VAMP4 VEZT VKORC1L1 YIPF6 ZDHHC15 ZNF202
Entrez ID		79415	219402
HPRD ID		14630	17609
Ensembl ID		ENSG00000178927	ENSG00000122033
Uniprot IDs		Q9BQA9	Q9H2K0
PDB IDs		8KEI	6NEQ 6NF8 6RW4 6RW5 7P2E 8QRM
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum Water Channel Activity Channel Activity Negative Regulation Of Cholesterol Import Steroid Dehydrogenase Activity Oxidoreductase Activity, Acting On NAD(P)H, Oxygen As Acceptor Regulation Of Cholesterol Import One-carbon Compound Transport Water Transport Superoxide-generating NADPH Oxidase Activity Identical Protein Binding Fluid Transport Lipid Droplet Ammonium Channel Activity Urea Transmembrane Transport	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Negative Regulation Of Sphingolipid Biosynthetic Process Serine Palmitoyltransferase Complex Regulation Of Transport Regulation Of Lipid Biosynthetic Process Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Synaptic Vesicle To Endosome Fusion Regulation Of Cellular Localization Granulocyte Migration Regulation Of Cholesterol Metabolic Process Regulation Of Membrane Lipid Metabolic Process Respiratory Burst After Phagocytosis Negative Regulation Of Lipid Metabolic Process Regulation Of Lipid Metabolic Process Negative Regulation Of Lipid Biosynthetic Process Neutrophil Migration Cholesterol Import Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Cholesterol Metabolic Process Myeloid Leukocyte Migration
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