AREG and WDR92

Number of citations of the paper that reports this interaction (PMID 23844004)
1

Data Source:
BioGRID (unspecified method)

		AREG	WDR92
Gene Name		amphiregulin	WD repeat domain 92
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cell Surface Integral Component Of Membrane
	Molecular Function	Cytokine Activity Epidermal Growth Factor Receptor Binding Protein Binding Growth Factor Activity	Protein Binding Methylated Histone Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Cell Proliferation Positive Regulation Of Cell Proliferation Glial Cell Proliferation Neuron Projection Development Response To Estradiol Positive Regulation Of Phosphorylation Response To Hydrogen Peroxide Response To Peptide Hormone Negative Regulation Of Osteoblast Differentiation Positive Regulation Of DNA Replication Response To Glucocorticoid Response To CAMP Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Mammary Gland Branching Involved In Thelarche Mammary Gland Alveolus Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation	Apoptotic Process Histone Lysine Methylation
Pathways
Drugs
Diseases
GWAS		Breast size ( 22747683)	Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Protein-Protein Interactions		8 interactors: APP CCND3 EGFR KRTAP10-3 MMP9 UBQLN4 WDR92 WT1	1 interactors: AREG
Entrez ID		374	116143
HPRD ID		00093	14012
Ensembl ID		ENSG00000109321	ENSG00000243667
Uniprot IDs		P15514	Q96MX6
PDB IDs		2RNL	3I2N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Morphogenesis Involved In Differentiation Positive Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cell Morphogenesis Axon Guidance Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Locomotion Regulation Of ERBB Signaling Pathway Reproductive Process Alkanesulfonate Metabolic Process Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Axonogenesis Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Visceral Serous Pericardium Development Synaptic Growth At Neuromuscular Junction Posterior Mesonephric Tubule Development Adrenal Cortex Formation Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Metanephric Ureteric Bud Development Thorax And Anterior Abdomen Determination Astrocyte Activation Neuron Projection Morphogenesis Cell Activation Regulation Of Protein Binding Negative Regulation Of Glomerular Mesangial Cell Proliferation Negative Regulation Of Glomerulus Development Collateral Sprouting In Absence Of Injury Regulation Of Protein Kinase Activity Cell Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Positive Regulation Of Receptor Binding Activation Of Phospholipase A2 Activity Zygotic Determination Of Anterior/posterior Axis, Embryo Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Keratinocyte Migration Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Proliferation Involved In Kidney Development Cell Projection Morphogenesis Cell Part Morphogenesis	Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Mammary Gland Branching Involved In Thelarche Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Branch Elongation Involved In Mammary Gland Duct Branching Development Of Secondary Female Sexual Characteristics Development Of Secondary Sexual Characteristics Glial Cell Proliferation Mammary Gland Epithelial Cell Proliferation Branch Elongation Of An Epithelium Axis Elongation Mammary Gland Alveolus Development Mammary Gland Lobule Development Negative Regulation Of Osteoblast Differentiation Branching Involved In Mammary Gland Duct Morphogenesis Mammary Gland Duct Morphogenesis Positive Regulation Of DNA Replication Negative Regulation Of Ossification Mammary Gland Morphogenesis Epithelial Cell Proliferation Mammary Gland Epithelium Development Response To Estradiol Response To CAMP Response To Hydrogen Peroxide Regulation Of DNA Replication Regulation Of Osteoblast Differentiation Developmental Growth Involved In Morphogenesis Positive Regulation Of DNA Metabolic Process Response To Organophosphorus Response To Glucocorticoid Gland Morphogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Corticosteroid Mammary Gland Development Response To Purine-containing Compound Response To Reactive Oxygen Species Regulation Of Ossification Branching Morphogenesis Of An Epithelial Tube Response To Estrogen Morphogenesis Of A Branching Epithelium Gliogenesis Morphogenesis Of A Branching Structure Developmental Growth Epithelial Tube Morphogenesis Response To Oxidative Stress Tube Morphogenesis Response To Peptide Hormone Response To Inorganic Substance Response To Steroid Hormone Response To Peptide
Tagcloud ?		18k amphiregulin atf3 biomarker biomarkers bleomycin candidate chemotherapy cisplatin clustered damage endothelial equalled etoposide gdf hmec hscrp mellitus micro microarrays preclinical qrt sets testicular unbiased untreated von vwf willebrand
Tagcloud (Difference) ?		18k amphiregulin atf3 biomarker biomarkers bleomycin candidate chemotherapy cisplatin clustered damage endothelial equalled etoposide gdf hmec hscrp mellitus micro microarrays preclinical qrt sets testicular unbiased untreated von vwf willebrand
Tagcloud (Intersection) ?