AREG

Gene Name		amphiregulin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cell Surface Integral Component Of Membrane
	Molecular Function	Cytokine Activity Epidermal Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Cell Proliferation Positive Regulation Of Cell Proliferation Glial Cell Proliferation Neuron Projection Development Response To Estradiol Positive Regulation Of Phosphorylation Response To Hydrogen Peroxide Response To Peptide Hormone Negative Regulation Of Osteoblast Differentiation Positive Regulation Of DNA Replication Response To Glucocorticoid Response To CAMP Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis Mammary Gland Branching Involved In Thelarche Mammary Gland Alveolus Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Pathways
Drugs
Diseases
GWAS		Breast size ( 22747683)
Protein-protein Interactions		8 interactors: APP CCND3 EGFR KRTAP10-3 MMP9 UBQLN4 WDR92 WT1
Entrez ID		374
HPRD ID		00093
Ensembl ID		ENSG00000109321
Uniprot IDs		P15514
PDB IDs		2RNL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Morphogenesis Involved In Differentiation Positive Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cell Morphogenesis Axon Guidance Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Locomotion Regulation Of ERBB Signaling Pathway Reproductive Process Alkanesulfonate Metabolic Process Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Axonogenesis Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Axon Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Visceral Serous Pericardium Development Synaptic Growth At Neuromuscular Junction Posterior Mesonephric Tubule Development Adrenal Cortex Formation Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of Metanephric Ureteric Bud Development Thorax And Anterior Abdomen Determination Astrocyte Activation Neuron Projection Morphogenesis Cell Activation Regulation Of Protein Binding Negative Regulation Of Glomerular Mesangial Cell Proliferation Negative Regulation Of Glomerulus Development Collateral Sprouting In Absence Of Injury Regulation Of Protein Kinase Activity Cell Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Positive Regulation Of Receptor Binding Activation Of Phospholipase A2 Activity Zygotic Determination Of Anterior/posterior Axis, Embryo Regulation Of Kinase Activity Neuron Projection Development Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Keratinocyte Migration Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Proliferation Involved In Kidney Development Cell Projection Morphogenesis Cell Part Morphogenesis
Tagcloud ?		18k amphiregulin atf3 biomarker biomarkers bleomycin candidate chemotherapy cisplatin clustered damage endothelial equalled etoposide gdf hmec hscrp mellitus micro microarrays preclinical qrt sets testicular unbiased untreated von vwf willebrand