LGALS14 and IKZF3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LGALS14	IKZF3
Gene Name		lectin, galactoside-binding, soluble, 14	IKAROS family zinc finger 3 (Aiolos)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Carbohydrate Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Apoptotic Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		15 interactors: ADAMTSL4 BANP CRLF3 FCHO1 FLNA GFAP IKZF3 LNX1 MID2 REL SDCBP2 SPAG5 TCF4 TNR TRIM27	71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT
Entrez ID		56891	22806
HPRD ID		06268	05869
Ensembl ID		ENSG00000006659
Uniprot IDs		Q8TCE9	Q9UKT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Growth Long-term Synaptic Potentiation Positive Regulation Of Schwann Cell Proliferation Negative Regulation Of Axon Extension Involved In Regeneration Regulation Of Cellular Component Organization Positive Regulation Of Signal Transduction Regulation Of Viral Transcription Negative Regulation Of Viral Process Cell Cycle Regulation Of Protein Localization Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Developmental Growth Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Signaling Organelle Organization Transcription, DNA-templated Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Glial Cell Development Regulation Of Gliogenesis Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleocytoplasmic Transport RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Synaptic Transmission Cellular Localization Negative Regulation Of Protein Catabolic Process Maintenance Of DNA Repeat Elements Negative Regulation Of Neuron Projection Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Metabolic Process Spindle Organization Protein Complex Assembly Regulation Of Cellular Localization Cell Cycle Process Regulation Of Intracellular Signal Transduction Cytokine Production Negative Regulation Of Cell Projection Organization Cellular Macromolecule Biosynthetic Process Protein Localization To Organelle	Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound
Tagcloud ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?