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LGALS14 and REL
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
LGALS14
REL
Gene Name
lectin, galactoside-binding, soluble, 14
v-rel avian reticuloendotheliosis viral oncogene homolog
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytosol
I-kappaB/NF-kappaB Complex
Molecular Function
Carbohydrate Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Biological Process
Apoptotic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cytokine Production
Transcription, DNA-templated
Inflammatory Response
I-kappaB Kinase/NF-kappaB Signaling
Response To Cytokine
NIK/NF-kappaB Signaling
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Interleukin-12 Biosynthetic Process
Innate Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Neuron Death
Pathways
Signaling by the B Cell Receptor (BCR)
Downstream signaling events of B Cell Receptor (BCR)
Activation of NF-kappaB in B cells
Adaptive Immune System
Drugs
Diseases
GWAS
Celiac disease (
20190752
)
Crohn's disease (
22412388
21102463
)
Hodgkin's lymphoma (
21037568
)
Inflammatory bowel disease (
23128233
)
Psoriasis (
20953190
)
Psoriatic arthritis (
22170493
)
Rheumatoid arthritis (
20453842
19503088
)
Ulcerative colitis (
20228799
)
Protein-Protein Interactions
15 interactors:
ADAMTSL4
BANP
CRLF3
FCHO1
FLNA
GFAP
IKZF3
LNX1
MID2
REL
SDCBP2
SPAG5
TCF4
TNR
TRIM27
201 interactors:
A1CF
AAAS
ACOT8
ACTN3
ADRB2
ADSL
AES
AGPAT4
ALOX5
AR
ARIH2
ARNT2
ASAP3
ATG9A
ATPAF2
ATXN1
BARHL2
BID
BMF
BZRAP1
C11orf68
C12orf75
C1orf109
C20orf195
C9orf72
C9orf91
CABP5
CALM1
CCNE1
CCNJL
CDKN2C
CEP19
CGGBP1
CHAF1A
CHCHD2
CIB3
CINP
CKS1B
CLIC4
COL20A1
COL8A1
CPNE2
CPSF1
CTNNBIP1
CXCL14
DAAM2
DGCR6
DHPS
DMRT3
DNTT
DPF2
DYNC1LI1
EFHC1
EGLN3
EIF3A
EIF3D
EIF4E2
EIF4EBP1
EIF5A
EIF5A2
ELF1
EML2
EP300
EPHB6
EPM2AIP1
EXOSC1
EXOSC5
EXOSC8
FHIT
FHL2
FKBP1B
FLAD1
FLNA
FOXO4
FUT11
GADD45G
GLYCTK
GRB2
GTF2B
HAT1
HDAC7
HIP1
HLA-DOA
HSPA4
HSPA8
HSPB7
IL36RN
KIAA0100
KLHL32
KLHL40
KRTAP9-4
LASP1
LGALS14
LMO1
LMO2
LNPEP
LSM2
MAD2L2
MAGOHB
MAP3K7CL
MAP3K8
MAPK8
MEMO1
MIEN1
MORF4L1
MRPL10
MTPN
MVP
NAGK
NCK2
NDE1
NDUFAF3
NECAP1
NEDD9
NEIL2
NEUROG3
NFKB1
NFKB2
NFKBIA
NFKBIB
NFKBIE
NGB
NKRF
NME7
NOL9
NOTCH1
NR2C2AP
NUCB1
NUDT14
NXT2
OAZ3
OSGIN1
OSTF1
OTUB2
OTUD4
PARK2
PARVG
PATE1
PIH1D2
PLCB4
PLEKHN1
POLE2
POLR1A
POLR2L
POP5
PPP4C
PRDM10
PRKAB2
PSMA1
PTGER3
PTK6
R3HDM2
RAB41
RABIF
RASSF5
RBM39
RECK
RELA
REXO1L6P
RIPPLY1
RNF213
RSPH14
SAT1
SDCBP
SEC14L4
SEC31A
SEPT7
SIN3A
SLC39A13
SLC41A3
SLC6A12
SNRNP25
SP1
SRF
STK16
STRA13
SZT2
TBP
TDO2
TMEM165
TMEM8A
TNIP2
TNS2
TRAPPC2L
TRIM74
TSSC4
TSSK3
TSTD2
TTC19
TTC21A
TXNL4B
UBASH3A
UBE2K
UBE2Z
VPS25
ZDHHC24
ZNF417
ZNF550
ZNF564
ZNF572
ZNF765
Entrez ID
56891
5966
HPRD ID
06268
01286
Ensembl ID
ENSG00000006659
ENSG00000162924
Uniprot IDs
Q8TCE9
Q04864
Q17RU2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Viral Release From Host Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Viral Transcription
Regulation Of Viral Release From Host Cell
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Growth
Long-term Synaptic Potentiation
Positive Regulation Of Schwann Cell Proliferation
Negative Regulation Of Axon Extension Involved In Regeneration
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Regulation Of Viral Transcription
Negative Regulation Of Viral Process
Cell Cycle
Regulation Of Protein Localization
Negative Regulation Of Interleukin-2 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Developmental Growth
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Signaling
Organelle Organization
Transcription, DNA-templated
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Glial Cell Development
Regulation Of Gliogenesis
Regulation Of Transcription, DNA-templated
Positive Regulation Of Nucleocytoplasmic Transport
RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Synaptic Transmission
Cellular Localization
Negative Regulation Of Protein Catabolic Process
Maintenance Of DNA Repeat Elements
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of RNA Metabolic Process
Spindle Organization
Protein Complex Assembly
Regulation Of Cellular Localization
Cell Cycle Process
Regulation Of Intracellular Signal Transduction
Cytokine Production
Negative Regulation Of Cell Projection Organization
Cellular Macromolecule Biosynthetic Process
Protein Localization To Organelle
Gene Expression
RNA Metabolic Process
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Gene Expression
Cellular Process
Regulation Of Cellular Protein Metabolic Process
Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Toll-like Receptor 2 Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Toll-like Receptor 9 Signaling Pathway
Apoptotic Process
Cell Death
Toll-like Receptor 3 Signaling Pathway
Death
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Programmed Cell Death
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Peptidyl-lysine Modification To Peptidyl-hypusine
Positive Regulation Of Type I Interferon Production
Regulation Of RNA Metabolic Process
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Posttranscriptional Regulation Of Gene Expression
Cellular Response To Stimulus
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
chorionic
commercial
complementary
crude
deoxynucleotidyl
deoxyuridine
digoxigenin
exhibiting
fractions
furthered
go
gonadotropin
haf
hcg
immunodeficiency
inoculation
kaposi
ks
neoplastic
nick
preceded
pregnancy
preparations
sarcoma
slk
transferase
triphosphate
tunel
y
Tagcloud (Difference)
?
chorionic
commercial
complementary
crude
deoxynucleotidyl
deoxyuridine
digoxigenin
exhibiting
fractions
furthered
go
gonadotropin
haf
hcg
immunodeficiency
inoculation
kaposi
ks
neoplastic
nick
preceded
pregnancy
preparations
sarcoma
slk
transferase
triphosphate
tunel
y
Tagcloud (Intersection)
?