LGALS14 and TBC1D25

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LGALS14	TBC1D25
Description		galectin 14	TBC1 domain family member 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm Autophagosome Cytoplasmic Vesicle
	Molecular Function	Protein Binding Carbohydrate Binding	GTPase Activator Activity Protein Binding
	Biological Process	Apoptotic Process	Autophagy Regulation Of Autophagosome Maturation
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Sum eosinophil basophil counts ( 27863252)
Interacting Genes		47 interacting genes: ADAMTSL4 AJUBA BANP BLZF1 C1QTNF2 CFTR COG6 CRLF3 DDIT4L DOK6 FCHO1 FLACC1 FLNA GFAP IKZF3 IL16 JRK KRT19 KRT35 LNX1 LNX2 MEI4 MID2 NFKBID PCBD2 PICK1 POF1B PPM1J REL RIMBP3C SDCBP2 SH3GLB2 SPAG5 STAT5B TARS3 TBC1D25 TCF4 TEKT1 TEPSIN TNR TRIM23 TRIM27 VIM ZBTB8A ZNF438 ZNF655 ZNF71	17 interacting genes: FAM9B FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 HMGB2 KCNIP1 LARP1B LGALS14 LMNTD2 MAP1LC3A MAP1LC3B MAP1LC3C RAB2A RUSC1 TRIML2
Entrez ID		56891	4943
HPRD ID		06268	08948
Ensembl ID		ENSG00000006659	ENSG00000068354
Uniprot IDs		Q8TCE9	B4DF03 Q3MII6
PDB IDs		6K2Y 6K2Z
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Membrane Autophagosome Maturation Mitophagy Autophagy Of Mitochondrion Macroautophagy Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly Autophagy Vacuole Organization Cellular Response To Starvation Microtubule Response To Starvation Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding GABA Receptor Binding Cytoplasmic Vesicle Organelle Assembly Response To Nutrient Levels Beta-tubulin Binding Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Organelle Membrane Cytoskeleton Organelle Organization Negative Regulation Of Autophagosome Assembly Cellular Response To Stress Microtubule Binding Endomembrane System Positive Regulation Of Protein Polyubiquitination Transcription Factor Binding Extrinsic Apoptotic Signaling Pathway Cytoplasm Protein-containing Complex Organization Regulation Of Protein Polyubiquitination Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Catabolic Process Gamma-tubulin Binding Negative Regulation Of Macroautophagy Positive Regulation Of Interferon-beta Production Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Autophagosome Assembly Cellular Component Assembly Regulation Of Interferon-beta Production Golgi Apparatus Regulation Of Vacuole Organization
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