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CCL28 and ACKR2
Number of citations of the paper that reports this interaction (PMID
10781587
)
35
Data Source:
HPRD
(in vivo)
CCL28
ACKR2
Gene Name
chemokine (C-C motif) ligand 28
atypical chemokine receptor 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Vesicular Exosome
Early Endosome
Actin Filament
Plasma Membrane
Integral Component Of Plasma Membrane
Recycling Endosome
Molecular Function
Chemokine Activity
Chemokine Receptor Activity
Scavenger Receptor Activity
C-C Chemokine Receptor Activity
C-X-C Chemokine Receptor Activity
C-C Chemokine Binding
Biological Process
Positive Regulation Of Cell-matrix Adhesion
Chemotaxis
Immune Response
Positive Regulation Of Cytosolic Calcium Ion Concentration
Response To Nutrient
Cell Chemotaxis
Negative Regulation Of Leukocyte Tethering Or Rolling
Receptor-mediated Endocytosis
Chemotaxis
Inflammatory Response
Immune Response
G-protein Coupled Receptor Signaling Pathway
Multicellular Organismal Development
Neutrophil Activation
Chemokine-mediated Signaling Pathway
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Peptide ligand-binding receptors
Chemokine receptors bind chemokines
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Peptide ligand-binding receptors
Chemokine receptors bind chemokines
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
ACKR2
CCR10
CCR3
DDI1
PSMA3
STUB1
16 interactors:
APP
CCL11
CCL13
CCL14
CCL19
CCL2
CCL21
CCL25
CCL27
CCL28
CCL3
CCL3L3
CCL4
CCL5
CCL7
CCL8
Entrez ID
56477
1238
HPRD ID
05577
09095
Ensembl ID
ENSG00000144648
Uniprot IDs
A0N0Q3
Q9NRJ3
O00590
PDB IDs
Enriched GO Terms of Interacting Partners
?
Chemokine-mediated Signaling Pathway
Neutrophil Activation
Inflammatory Response
Cytokine-mediated Signaling Pathway
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Cellular Response To Cytokine Stimulus
Chemotaxis
Response To Stress
Positive Regulation Of Protein Ubiquitination
Response To Cytokine
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Cellular Response To Organic Substance
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Cytosolic Calcium Ion Concentration
Protein Polyubiquitination
Cytosolic Calcium Ion Homeostasis
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Catabolic Process
Response To Organic Substance
Ubiquitin-dependent SMAD Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
G-protein Coupled Receptor Signaling Pathway
Cellular Calcium Ion Homeostasis
Positive Regulation Of Proteolysis
Calcium Ion Homeostasis
Locomotion
Signal Transduction
Regulation Of Glucocorticoid Metabolic Process
Defense Response
Receptor-mediated Endocytosis
Misfolded Or Incompletely Synthesized Protein Catabolic Process
Cellular Response To Misfolded Protein
Cell Surface Receptor Signaling Pathway
Signaling
Regulation Of Protein Catabolic Process
Cell Communication
Response To Misfolded Protein
Cellular Metal Ion Homeostasis
Proteolysis
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Metal Ion Homeostasis
Leukocyte Activation
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Cellular Chemical Homeostasis
Cell Chemotaxis
Chemotaxis
Cell Migration
Locomotion
Immune Response
Cell Motility
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
Movement Of Cell Or Subcellular Component
Cellular Metal Ion Homeostasis
Inflammatory Response
Response To External Stimulus
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Metal Ion Homeostasis
Regulation Of Leukocyte Migration
Cellular Chemical Homeostasis
Immune System Process
Ion Homeostasis
Cellular Homeostasis
Leukocyte Chemotaxis
Eosinophil Chemotaxis
Leukocyte Migration
Chemical Homeostasis
Eosinophil Migration
Positive Regulation Of Leukocyte Chemotaxis
Regulation Of Lymphocyte Migration
Defense Response
Positive Regulation Of Leukocyte Migration
Positive Regulation Of Chemotaxis
Positive Regulation Of Natural Killer Cell Chemotaxis
Regulation Of Cell Migration
Positive Regulation Of Behavior
Regulation Of Cell Motility
Granulocyte Chemotaxis
Regulation Of Chemotaxis
Homeostatic Process
Regulation Of Locomotion
Regulation Of Cellular Component Movement
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Regulation Of Behavior
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Monocyte Chemotaxis
Negative Regulation Of Leukocyte Tethering Or Rolling
Negative Regulation Of Leukocyte Migration
Cellular Response To Stimulus
Response To Stress
Regulation Of Granulocyte Chemotaxis
Tagcloud
?
17f
28a
6ckine
ccl13
ccl14
ccl16
ccl17
ccl18
ccl19
ccl21
ccl22
ccl23
ccl25
ccl26
ccl27
ccl7
ccl8
ctack
cxcl11
cxcl3
cxcl7
il18
lymphotactin
mpif
parc
tarc
teck
tnfsf14
xcl1
Tagcloud (Difference)
?
17f
28a
6ckine
ccl13
ccl14
ccl16
ccl17
ccl18
ccl19
ccl21
ccl22
ccl23
ccl25
ccl26
ccl27
ccl7
ccl8
ctack
cxcl11
cxcl3
cxcl7
il18
lymphotactin
mpif
parc
tarc
teck
tnfsf14
xcl1
Tagcloud (Intersection)
?