CCL28 and XCL2

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CCL28	XCL2
Description		C-C motif chemokine ligand 28	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Chemokine Receptor Binding CXCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Inflammatory Response Immune Response Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Neutrophil Chemotaxis Killing Of Cells Of Another Organism Cytolysis In Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide Negative Regulation Of Leukocyte Tethering Or Rolling	Chemotaxis Inflammatory Response Immune Response Signal Transduction Blood Circulation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Metabolite levels (X-11787) ( 23934736) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		56477	6846
HPRD ID		05577	05317
Ensembl ID		ENSG00000151882	ENSG00000143185
Uniprot IDs		A0N0Q3 D6RC73 Q9NRJ3	Q9UBD3
PDB IDs		6CWS
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemokine-mediated Signaling Pathway Cytokine Activity Humoral Immune Response Leukocyte Chemotaxis Cell Migration Granulocyte Chemotaxis Killing Of Cells Of Another Organism Cell Motility Myeloid Leukocyte Migration Granulocyte Migration Immune Response Leukocyte Migration Inflammatory Response Cell Killing Cytokine-mediated Signaling Pathway Immune System Process Defense Response To Symbiont CXCR Chemokine Receptor Binding Defense Response To Other Organism Defense Response CCR Chemokine Receptor Binding Response To Other Organism G Protein-coupled Receptor Signaling Pathway Mononuclear Cell Migration Extracellular Space Response To External Biotic Stimulus Neutrophil Chemotaxis Neutrophil Migration Response To Stress Positive Regulation Of T Cell Migration Regulation Of T Cell Chemotaxis Extracellular Region CXCR3 Chemokine Receptor Binding Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Chemotaxis Eosinophil Chemotaxis Positive Regulation Of Mononuclear Cell Migration Regulation Of T Cell Migration Eosinophil Migration Positive Regulation Of Cell Migration Regulation Of Lymphocyte Chemotaxis Lymphocyte Chemotaxis Signal Transduction	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Antimicrobial Humoral Response Locomotion Leukocyte Chemotaxis Cytokine Activity Leukocyte Migration Humoral Immune Response Granulocyte Chemotaxis Myeloid Leukocyte Migration Granulocyte Migration Cell Migration Inflammatory Response Cell Motility Defense Response To Symbiont Defense Response To Other Organism Mononuclear Cell Migration Immune Response Chemokine-mediated Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Defense Response Response To Other Organism CCR Chemokine Receptor Binding Immune System Process Extracellular Space Killing Of Cells Of Another Organism Regulation Of Leukocyte Migration CXCR Chemokine Receptor Binding Extracellular Region Response To External Biotic Stimulus Positive Regulation Of Leukocyte Migration Positive Regulation Of Mononuclear Cell Migration Cell Killing Monocyte Chemotaxis Regulation Of Lymphocyte Migration Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Cytokine-mediated Signaling Pathway Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Lymphocyte Migration Regulation Of Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Cell Motility Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Locomotion
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