CCL28 and CCL17

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CCL28	CCL17
Description		C-C motif chemokine ligand 28	C-C motif chemokine ligand 17
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Chemokine Receptor Binding CXCR Chemokine Receptor Binding	Signaling Receptor Binding Cytokine Activity Protein Binding Chemokine Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Inflammatory Response Immune Response Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Neutrophil Chemotaxis Killing Of Cells Of Another Organism Cytolysis In Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide Negative Regulation Of Leukocyte Tethering Or Rolling	Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Killing Of Cells Of Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines
Drugs
Diseases
GWAS		Metabolite levels (X-11787) ( 23934736) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Blood protein levels ( 30072576) Thymus and reactivation regulated chemokine levels ( 33227023)
Interacting Genes		26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2	9 interacting genes: ACKR1 CCL21 CCL25 CCL26 CCL28 CCL5 CCR4 CCR8 VCAM1
Entrez ID		56477	6361
HPRD ID		05577	03309
Ensembl ID		ENSG00000151882	ENSG00000102970
Uniprot IDs		A0N0Q3 D6RC73 Q9NRJ3	Q92583
PDB IDs		6CWS	1NR2 1NR4 5WK3 7S4N 7SCV 8FJ2 8SKK
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemokine-mediated Signaling Pathway Cytokine Activity Humoral Immune Response Leukocyte Chemotaxis Cell Migration Granulocyte Chemotaxis Killing Of Cells Of Another Organism Cell Motility Myeloid Leukocyte Migration Granulocyte Migration Immune Response Leukocyte Migration Inflammatory Response Cell Killing Cytokine-mediated Signaling Pathway Immune System Process Defense Response To Symbiont CXCR Chemokine Receptor Binding Defense Response To Other Organism Defense Response CCR Chemokine Receptor Binding Response To Other Organism G Protein-coupled Receptor Signaling Pathway Mononuclear Cell Migration Extracellular Space Response To External Biotic Stimulus Neutrophil Chemotaxis Neutrophil Migration Response To Stress Positive Regulation Of T Cell Migration Regulation Of T Cell Chemotaxis Extracellular Region CXCR3 Chemokine Receptor Binding Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Chemotaxis Eosinophil Chemotaxis Positive Regulation Of Mononuclear Cell Migration Regulation Of T Cell Migration Eosinophil Migration Positive Regulation Of Cell Migration Regulation Of Lymphocyte Chemotaxis Lymphocyte Chemotaxis Signal Transduction	Chemokine-mediated Signaling Pathway Cell Chemotaxis Chemotaxis Locomotion Inflammatory Response Chemokine Receptor Binding Chemokine Activity Cytokine-mediated Signaling Pathway Granulocyte Chemotaxis Eosinophil Chemotaxis Eosinophil Migration Negative Regulation Of Leukocyte Tethering Or Rolling Cell Migration Granulocyte Migration CCR Chemokine Receptor Binding Cell Motility Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Leukocyte Chemotaxis Negative Regulation Of Cellular Extravasation Antimicrobial Humoral Response Defense Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Cytokine Activity Regulation Of Leukocyte Tethering Or Rolling Leukocyte Migration Humoral Immune Response Immune System Process C-C Chemokine Binding Immune Response Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Cellular Extravasation Cellular Response To Cytokine Stimulus Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Negative Regulation Of Leukocyte Migration Regulation Of Leukocyte Migration Positive Regulation Of Cell-matrix Adhesion Response To Cytokine Response To Peptide Cell Surface Receptor Signaling Pathway Response To Stress Response To External Biotic Stimulus Defense Response To Symbiont Defense Response To Other Organism Mononuclear Cell Migration Positive Regulation Of T Cell Chemotaxis Regulation Of Cell Adhesion
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