ACKR2 and CCL27

Number of citations of the paper that reports this interaction (PMID 11821900)
79

Data Source:
HPRD (in vivo)

		ACKR2	CCL27
Gene Name		atypical chemokine receptor 2	chemokine (C-C motif) ligand 27
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Actin Filament Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Receptor Activity Scavenger Receptor Activity C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding	Chemokine Activity
	Biological Process	Receptor-mediated Endocytosis Chemotaxis Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Neutrophil Activation Chemokine-mediated Signaling Pathway	Chemotaxis Immune Response Cell-cell Signaling Cell Chemotaxis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP CCL11 CCL13 CCL14 CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL3 CCL3L3 CCL4 CCL5 CCL7 CCL8	2 interactors: ACKR2 CCR10
Entrez ID		1238	10850
HPRD ID		09095	05321
Ensembl ID		ENSG00000144648	ENSG00000213927
Uniprot IDs		O00590	Q5VZ77 Q9Y4X3
PDB IDs			2KUM
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Chemotaxis Cell Migration Locomotion Immune Response Cell Motility Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Movement Of Cell Or Subcellular Component Cellular Metal Ion Homeostasis Inflammatory Response Response To External Stimulus Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Immune System Process Ion Homeostasis Cellular Homeostasis Leukocyte Chemotaxis Eosinophil Chemotaxis Leukocyte Migration Chemical Homeostasis Eosinophil Migration Positive Regulation Of Leukocyte Chemotaxis Regulation Of Lymphocyte Migration Defense Response Positive Regulation Of Leukocyte Migration Positive Regulation Of Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis Regulation Of Cell Migration Positive Regulation Of Behavior Regulation Of Cell Motility Granulocyte Chemotaxis Regulation Of Chemotaxis Homeostatic Process Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Behavior Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Monocyte Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling Negative Regulation Of Leukocyte Migration Cellular Response To Stimulus Response To Stress Regulation Of Granulocyte Chemotaxis	Neutrophil Activation Chemokine-mediated Signaling Pathway Receptor-mediated Endocytosis Inflammatory Response Cytokine-mediated Signaling Pathway Leukocyte Activation Cellular Response To Cytokine Stimulus Chemotaxis Endocytosis Cell Activation Response To Cytokine G-protein Coupled Receptor Signaling Pathway Locomotion Immune Response Defense Response Vesicle-mediated Transport Response To External Stimulus Cellular Response To Organic Substance Immune System Process Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Cell Surface Receptor Signaling Pathway Response To Stress Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis
Tagcloud ?			classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate
Tagcloud (Difference) ?			classifier consisting constructed correct costly distinguish easy eczema era goal handle insight investigating misdiagnosed nos2 occasionally omics opposed pathogeneses personalized predicts psoriasis reach reliably signature simultaneously technologies throughput ultimate
Tagcloud (Intersection) ?