CCAR1 and CHERP

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		CCAR1	CHERP
Description		cell division cycle and apoptosis regulator 1	calcium homeostasis endoplasmic reticulum protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding Protein Binding Transmembrane Transporter Binding
	Biological Process	Regulation Of DNA-templated Transcription Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Cell Population Proliferation Protein Ubiquitination Positive Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription	RNA Processing Intracellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cannabis dependence symptom count ( 27028160)
Interacting Genes		18 interacting genes: CASP10 CHERP CTNNB1 DNAAF6 GOLGA2 HMGB1 HNRNPK HUNK MDM2 MIR106B MIRLET7G MTUS2 RBM10 RNF10 RNF113A SFN U2AF2 USP7	48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MECOM MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 USP54 WBP4
Entrez ID		55749	10523
HPRD ID		10811	13051
Ensembl ID		ENSG00000060339	ENSG00000085872
Uniprot IDs		Q8IX12	Q8IWX8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Glycoprotein Biosynthetic Process Regulation Of Intracellular Transport Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nucleocytoplasmic Transport Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Vasculature Development Disordered Domain Specific Binding Cadherin Binding Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Protein Ubiquitination Regulation Of Intracellular Signal Transduction Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Cell Population Proliferation Protein Modification By Small Protein Conjugation Epithelial Cell Proliferation Glial Cell Fate Determination Regulation Of Protein Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Gliogenesis Positive Regulation Of Angiogenesis Regulation Of Myelination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Vasculature Development D-serine Catabolic Process Glycine Oxidase Activity D-amino-acid Dehydrogenase Activity D-alanine Catabolic Process Regulation Of Protein Export From Nucleus Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of Gene Expression, Epigenetic	RNA Splicing MRNA Processing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Regulation Of MRNA Splicing, Via Spliceosome MiRNA-mediated Post-transcriptional Gene Silencing Nucleic Acid Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Nuclear Speck Regulation Of MRNA Processing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RNA Metabolic Process Spliceosomal Complex RS Domain Binding U1 SnRNP Binding Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process MRNA Cis Splicing, Via Spliceosome U2-type Precatalytic Spliceosome U2-type Prespliceosome Negative Regulation Of Macromolecule Biosynthetic Process U1 SnRNP Precatalytic Spliceosome Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Extracellular Vesicle Nucleobase-containing Compound Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Gene Expression
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