CCAR1 and MIRLET7G

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		CCAR1	MIRLET7G
Description		cell division cycle and apoptosis regulator 1	microRNA let-7g
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytoplasm Perinuclear Region Of Cytoplasm	Extracellular Space RISC Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Ubiquitin Protein Ligase Activity	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of DNA-templated Transcription Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Cell Population Proliferation Protein Ubiquitination Positive Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription	Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Cellular Response To Glucose Stimulus Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Cannabis dependence symptom count ( 27028160)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 23974872)
Interacting Genes		18 interacting genes: CASP10 CHERP CTNNB1 DNAAF6 GOLGA2 HMGB1 HNRNPK HUNK MDM2 MIR106B MIRLET7G MTUS2 RBM10 RNF10 RNF113A SFN U2AF2 USP7	116 interacting genes: ADARB1 APOBEC3B AQR ATXN2L C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PAXBP1 PDCD11 PLOD1 PLRG1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RBM4B RBM5 RBM6 RBMS1 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SF3B5 SFPQ SPOUT1 STRBP SUGP1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR
Entrez ID		55749	406890
HPRD ID		10811
Ensembl ID		ENSG00000060339	ENSG00000199150
Uniprot IDs		Q8IX12
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Glycoprotein Biosynthetic Process Regulation Of Intracellular Transport Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Nucleocytoplasmic Transport Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Vasculature Development Disordered Domain Specific Binding Cadherin Binding Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Protein Ubiquitination Regulation Of Intracellular Signal Transduction Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Negative Regulation Of Cell Population Proliferation Protein Modification By Small Protein Conjugation Epithelial Cell Proliferation Glial Cell Fate Determination Regulation Of Protein Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Gliogenesis Positive Regulation Of Angiogenesis Regulation Of Myelination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Vasculature Development D-serine Catabolic Process Glycine Oxidase Activity D-amino-acid Dehydrogenase Activity D-alanine Catabolic Process Regulation Of Protein Export From Nucleus Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of Gene Expression, Epigenetic	RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process MRNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Macromolecule Metabolic Process Regulation Of RNA Splicing Nucleoplasm Regulation Of MRNA Metabolic Process Nucleus Catalytic Step 2 Spliceosome Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Regulation Of Translation MRNA 3'-UTR Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of RNA Stability Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Spliceosomal Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of MRNA Catabolic Process U2 SnRNP RNA Stabilization MRNA Stabilization Negative Regulation Of Translation Regulation Of Metabolic Process MiRNA Processing Protein-RNA Complex Assembly TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity U2-type Prespliceosome Assembly Negative Regulation Of Macromolecule Metabolic Process
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