TRIM23 and SNRPB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIM23	SNRPB2
Description		tripartite motif containing 23	small nuclear ribonucleoprotein polypeptide B2
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GO Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Endomembrane System Membrane	Fibrillar Center Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP Nuclear Speck Cytoplasmic Ribonucleoprotein Granule U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Spliceosomal SnRNP Complex Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Transferase Activity GDP Binding Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding Protein Binding U1 SnRNA Binding
	Biological Process	Immune System Process Intracellular Protein Transport Positive Regulation Of Autophagy Vesicle-mediated Transport Protein Ubiquitination Innate Immune Response	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Food allergy (maternal genetic effects) ( 29489655) Metabolite levels ( 23823483) Response to haloperidol in schizophrenia ( 29503163)
Interacting Genes		219 interacting genes: ACTN4 AKTIP ANKRD36BP1 ANKRD55 ANO1 AP3M1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 BAZ2B BICRAL BRME1 C8orf33 CARD9 CATSPERT CBX8 CCDC13 CCDC146 CCDC25 CCDC33 CDC20B CDC73 CDR2 CFAP53 CHP1P2 CIMIP4 COX5B CPNE7 CREB5 CSRP2 CWF19L2 CXCL14 CYTH1 CYTH2 DCX DEPP1 DMC1 DMRT3 DNAAF4 DOCK2 EAF2 EHHADH EIF3D ENKD1 EPN2 EXOC3-AS1 FAM110A FAM133A FAM193B FAM83A FAM90A1 FBF1 FHIT FLAD1 FXR2 GAD1 GATA2 GCC2-AS1 GEM GGA2 GGA3 GLIDR GMCL2 GPANK1 GPKOW HAPLN2 HAUS1 HGS HNRNPLL HOXB5 HSPB7 IL16 IQCE IQUB JOSD1 JRK KAT5 KIFC3 KLHL42 KRT6A KRT75 KRT76 LAGE3 LENG1 LGALS14 LGALS3 LGALS8 LINC00526 LINC01018 LMO2 LMO3 LNX1 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MSRB3 MTFR2 MYEF2 MYOM1 MYOZ1 NAB2 NEDD9 NEK6 NFU1 NOXA1 NTAQ1 NUDT21 NXT2 PDE4D PHF1 PIAS2 PIK3R2 PITX1 PKP4 PLEKHA2 POLI POLL POM121 PPIL2 PPP1R15B PPP1R18 PRPF18 PRPF31 PSMA1 PSMB1 RAD18 RAMAC RCAN3 RIBC1 RIBC2 RIN1 RNF126 RNF213 RNF32 RNF34 RNF6 RSRC2 RTP5 RUFY1 SCNM1 SF1 SH2D4A SIAH1 SIRPA SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SNRPB2 SNW1 SORBS3 SPG21 SUMO1P1 TACO1 TASOR2 TBC1D22B TCEA2 TCEANC TEPSIN TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TRIM55 TRIM63 TROAP TSEN54 TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U UBE2W UBOX5 UBQLN1 USP2 USP20 USP21 UTP23 VGLL1 WDR25 WHR1 ZBTB16 ZBTB4 ZC2HC1C ZFAND2A ZNF20 ZNF250 ZNF408 ZNF417 ZNF474 ZNF564 ZNF581 ZNF587 ZNF688 ZNF835	26 interacting genes: ALAS1 CALM1 CEBPA CMTM6 DHX9 ERBB3 FOXP1 GABPB1 GABPB2 GOLGA2 HMBOX1 HNRNPUL1 HOMEZ HTATSF1 MCM6 MTUS2 NAP1L5 PICK1 PNMA1 PTEN SMN2 SNRPA1 SUGP1 TRIM23 TRIM27 ZBTB14
Entrez ID		373	6629
HPRD ID		03449	04628
Ensembl ID		ENSG00000113595	ENSG00000125870
Uniprot IDs		P36406	P08579
PDB IDs		5VZV 5VZW	1A9N 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7EVO 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 9FMD
Enriched GO Terms of Interacting Partners?		Protein Binding Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Ubiquitination Ubiquitin-protein Transferase Activity Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Nucleus Ubiquitin Protein Ligase Activity Proteolysis Involved In Protein Catabolic Process Protein K63-linked Ubiquitination Zinc Ion Binding Protein Modification Process Ubiquitin-protein Transferase Activator Activity Macromolecule Catabolic Process Protein Monoubiquitination Proteolysis Ubiquitin Protein Ligase Binding Protein K11-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin Binding SUMO Transferase Activity Spliceosomal Complex Nuclear Speck Proteasomal Protein Catabolic Process Macromolecule Metabolic Process Establishment Of Protein Localization To Vacuole MRNA Processing Spindle Pole Identical Protein Binding Protein Metabolic Process Metal Ion Binding SnRNP Binding Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Striated Muscle Myosin Thick Filament Cytoplasm Protein Sumoylation	Identical Protein Binding Nucleoplasm Nucleus RNA Splicing RNA Splicing, Via Transesterification Reactions Single-stranded 3'-5' DNA Helicase Activity RISC Complex Binding MRNA Metabolic Process CRD-mediated MRNA Stability Complex MRNA Processing Spliceosomal Complex Assembly Importin-alpha Family Protein Binding CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Stem-loop Binding Cytoplasmic Ribonucleoprotein Granule Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Meiotic Spindle Assembly Positive Regulation Of Cytoplasmic Translation DNA-templated Transcription Termination Regulation Of Viral Transcription Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Meiotic Spindle Organization Macromolecule Metabolic Process Transcription Cis-regulatory Region Binding Nucleic Acid Metabolic Process Alternative MRNA Splicing, Via Spliceosome PML Body U2-type Prespliceosome Assembly U2 SnRNP U2-type Spliceosomal Complex RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Dendritic Spine Organization Response To Stress Protein Binding Positive Regulation Of Biosynthetic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding 3'-5' DNA/RNA Helicase Activity Regulation Of Cytoplasmic Translation DNA-templated Viral Transcription Regulatory Region RNA Binding Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Organ Growth Regulation Of Actin Nucleation Telomere-telomerase Complex Assembly DNA Helicase Activity RNA Processing Nucleic Acid Binding
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