ASB10 and ANTXR1

Number of citations of the paper that reports this interaction (PubMedID 34285210)
58

Data Source:
BioGRID (two hybrid)

		ASB10	ANTXR1
Description		ankyrin repeat and SOCS box containing 10	ANTXR cell adhesion molecule 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane Lamellipodium Membrane Filopodium Membrane Cell Projection
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Collagen Binding Signaling Receptor Activity Metal Ion Binding Actin Filament Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	Blood Vessel Development Epidermal Growth Factor Receptor Signaling Pathway Actin Cytoskeleton Organization Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Assembly
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs			MDX-1303
Diseases
GWAS		Eyebrow thickness ( 26926045) Renal underexcretion gout ( 32238385)	Alzheimer's disease ( 30636644) Appendicular lean mass ( 33097823) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673) Height ( 21998595 31562340) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29235454 29617998 29785010 30054594 31959993) Orofacial cleft x maternal periconceptional multivitamin use interaction (1df) ( 33937227) Periodontitis (stage III/IV grade C) ( 33745150)
Interacting Genes		7 interacting genes: AGR3 ANTXR1 ARFGAP1 KDM1A LCN2 MEOX2 MRPL23	10 interacting genes: ASB10 BCL2L1 BRCA1 DTX3L HDAC2 LRP6 RBCK1 RNF182 TRIM35 TRIM51
Entrez ID		136371	84168
HPRD ID		10666	05913
Ensembl ID		ENSG00000146926	ENSG00000169604
Uniprot IDs		A0A090N8I2 Q8WXI3	H0YC24 Q53FL1 Q96EC6 Q9H6X2
PDB IDs			3N2N 6ADL 6ADM 6ADR 6CX1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Iron Ion Import Across Plasma Membrane Positive Regulation Of Hippocampal Neuron Apoptotic Process Enterobactin Binding Cellular Response To Ionizing Radiation Positive Regulation Of Endothelial Tube Morphogenesis Response To Toxic Substance Iron Ion Sequestering Activity Positive Regulation Of Cold-induced Thermogenesis Ribosomal Subunit Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Response To Herbicide Regulation Of Hippocampal Neuron Apoptotic Process Siderophore Transport Cytoplasmic Vesicle Lumen Response To Mycotoxin Regulation Of Cold-induced Thermogenesis Cellular Response To Radiation Negative Regulation Of Hippocampal Neuron Apoptotic Process Response To Kainic Acid Response To Ionizing Radiation Somite Specification MRF Binding Protein Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Regulation Of Iron Ion Transport Response To Blue Light Response To Fungicide Guanine Metabolic Process Regulation Of Endothelial Cell Migration Response To Iron(II) Ion Regulation Of Endothelial Tube Morphogenesis Histone H3K4 Demethylase Activity Cellular Response To X-ray Response To Fructose Histone H3K9 Demethylase Activity Negative Regulation Of Extracellular Matrix Assembly Dystroglycan Binding	Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Modification Process Response To Alcohol Ubiquitin-protein Transferase Activity Response To External Biotic Stimulus Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cell Cycle Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Other Organism Zinc Ion Binding Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Defense Response Response To Stress Apoptotic Process In Bone Marrow Cell Defense Response To Virus Protein Polyubiquitination Positive Regulation Of Male Mating Behavior Histone H4K91 Ubiquitin Ligase Activity Protein Autoubiquitination Cellular Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cell Cycle Negative Regulation Of Apoptotic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Protein De-2-hydroxyisobutyrylase Activity Response To Alkaloid Response To Virus Regulation Of Apoptotic Signaling Pathway Enzyme Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Damage Checkpoint Signaling Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Transferase Activity
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